Directory → Organotropona funds → Stomach funds → Antiemetic funds
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The groupProtivorvotnoe effect may have substance affecting different parts of the nervous regulation. In vomit caused by the local stomach irritation, obwolakiwate effective and cohesive funds, local anaesthetics.
Some neurotropic drugs reduce anxiety vomitoxin centre and hemoretseptorna launch zone. The latter contains dofaminove, holinergicakie (muskarinove) gistaminove (N_1) and serotoninove receptors, their blockade was effective.
Particularly important role in the development of vomiting, and the mechanism of action of antiemetics are serotoninove (5-NT_3) receptors. The impact on serotoninove (5-NT_3) receptors linked to ondansetrona, tropisetrona, effective with feces, protivoopujolevami caused by drugs (made possible to improve significantly the last dosing). Metoclopramide also impedes serotoninove (5-NT_3) receptors at the same time blocking dofaminove (D_2) receptors.
Holinolitiki, protivogistaminne drugs (dimedrol, diprazin, etc.) used in the prevention and treatment of sea and air sickness, disease Ménière. Protivorvotnami effective means neiroleptiki are from the group and fenotiazina butirofenon acting dofaminergicakie system. High protivorvotna activity in the series of derivatives fenotiazina have etaperazin, meterzin, triftazin, tietilperazin (torekan) et al. among butirofenonov - haloperidol, etc.