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AttSee also Acetylcysteine
Roman nameACC #
The composition and the form of1 package (3 g granulated) for the preparation of hot drink contains azetiltsisteina 200 or 600 mg; in a box 20 and 6 pcs. соответственно.1 package (3 g granulated) for solution for the reception inside the ацетилцистеина 100 or 200 mg; in a box 20 st.1 effervescent tablet is 100 mg (ATT 100), 200 mg (ATT 200) or 600 mg (ATT Long); tuba in the 20 and 50 pc. , in the bag 60 pc. (100 ATT, ATT 200), or 10 pcs. (ATT Long), in the box one dose or 1 sashe.1 ml solution for injection, 100 mg; in the sealed to 3 ml, in a cardboard bundle five vials.
Of drugsMukoliticescoe, soothing. Tearing disulfidnye connection acid mucopolysaccharides rates, slowing polymerization mukoproteidov and reduces mucus viscosity. Increases metabolism synthesis has detoksiciruuschee and antioxidant effects. Is safe withdrawal metabolita ziklofosfana (acrolein).
PharmacokineticsThe ingestion well absorbed from the digestive tract, bioavailability is about 10%, C_max achieved through 3h Linking blood plasma is about 50%. Write mainly kidneys in the form of active metabolites, a fraction of an unchanged to the faeces.
FarmakodinamikaAnise patients (including gnanuu) facilitates the provision contributes to the clearing. Step (to the inside) begins in 30 to 90 minutes and lasts 2-4 hours
IndicationsDiseases of the respiratory tract, causing high school thick mucus (acute and chronic bronchitis, including обструктивный, tracheitis, pneumonia, бронхоэктатическая disease, cystic fibrosis, etc.), ЛОР-заболевания (ларингит, синусит etc.), prevention of complications бронхолегочных (injured chest, broncho-трахеостомия, surgical practice), poisoning парацетамолом (as an antidote).
Pregnancy and lactationContraindicated. At the time of treatment should stop breastfeeding.
ContraindicationsHypersensitivity, the propensity to bleeding, saying the disease stomach and duodenal ulcers in the phase of deterioration, disease liver, kidneys, spleen, lung napochechnikov, pregnancy, breast-feeding.
Side-EffectsDiarrhoeal disorders, facial bleeding, noise in the winter, allergic reactions.
Specific guidanceMukoliticeski effect increasing additional admission liquid. Exceptionally prepared solution can be left on the 2-3 hours Using ATT should use glass dishes, and avoid contact with drug metals, rubber, oxygen, etc.
Patient interactionDo sossoudorasshirati etc. effects nitroglycerin.
PrecautionsYou can not combine with protivokashlevami means (possible stagnation in the respiratory passages due to the suppression of kashlevogo reflex). Admission antibiotics (inside), and ATT must separate notice (at least) interval. Not to be confused with antibiotics and proteoliticakimi enzymes in the solution for the m introduction. In a separate injections are at some distance from each other. Infants and children up to 1 year appointed only for health reasons (in the hospital under medical supervision). ATT Long appoint patients older than 14 years. The gnanom with bronchitis and cystic fibrosis should be combined with active evacuating patients with bronchitis obstruguom (cautiously) from bronholitikami. If treatment is not effective once weekly therapy should contact a doctor.
Dosing and AdministrationPills, PET : inwards after eating. The contents of one paketika dissolved in 1 glass of water, 1 schipuchuu tablets in 100 ml of water. Solution are referred. Adults and adolescents over 14 years in the 200 mg three times daily or 600 mg once a day. Children between 6 and 14 years in the 200 mg twice a day or 100 mg three times a day, from 2 to 5 years of age-100 mg 2-3 times a day, babies (from the 10th of the day), and children up to 2 years in the 50 mg 2-3 times a Sutki.pri fibrosis : patients weighing more than 30 kg to 800 mg / day; children over 6 years of age is up to 600 mg / day; from 2 to 6 years up to 400 mg / sut. Duration of treatment is 5-7 days (for chronic bronchitis and cystic fibrosis, for a longer time). Solution for injection : inhalation and 2-5 ml of 10% solution 3-4 times a day; Vnutribronhialnah for instillation-up to 300 mg / day; Vnutritrahealno-1 ml 10% solution every hour. B / m-adult-1-2 ml of 10% solution 2-3 times a day for children over the age of one year, 0.5-1 ml of 10% solution twice a day. The ATT can be used in / 386/1989
Storage conditionsgran.d / r-ra reception inside : At room температурегран.д/р-р�� for the reception inside : When temperature is not above 25 ° C
Shelf lifegran.d / r-ra reception inside : 3 g.gran.d / r-ra reception inside : 4 g.
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