Bromgexin-ferein

Roman name

Bromhexin-Ferein

The composition and the form of

5 ml syrup contain bromgexina 4 mg; in the glass bottle for 60 or 100 ml, in a cardboard bundle one bottle complete with measuring spoon.

Of drugs

Mukoliticescoe, skin, protivokashlevoe. Depolimerizuet acid polysaccharides rate and stimulates cells secretorne mucous membrane bronchi which produce secret containing neutral polysaccharides, reduces viscosity Bronchus secret and make its selection.

Pharmacokinetics

Once inside almost entirely (99%) in rats for 30 min. Bioavailability of 80%, has been associated with the plasma protein passes through the GEB and placental barrier. Metabolised in the liver, partly with the formation of active metabolites. T_1/2 to one hour, the terminal phase-15 hrs (from the back diffusion of tissue). Report the news, with multiple application can koumoulirovati. Against the backdrop of severe liver klirens lowered, and in chronic kidney failure, broken down metabolites.

Indications

Acute and chronic inflammatory diseases of the lungs, accompanied by the formation of trudnootdelema viscous sputum (bronchial asthma, cystic fibrosis, tuberculosis, pneumonia, traheobronhit, obstruguy bronchitis, bronhoektaza, emphysema lung disorders), trauma chest.

Contraindications

Hypersensitivity, I trimester of pregnancy, breast-feeding.

Side-Effects

Rarely, in a long reception, nausea, vomiting, diarrhoea phenomenon worsening ulcers stomach and duodenal ulcers, raising transaminaz in the serum, allergic reactions (skin rash, myalgia, etc.).

Specific guidance

Appointment against ulcers or stomach patients with stomach bleeding in the history warrant further medical controls.

Patient interaction

Products containing codeine impair releases razzyzenna patients. Is penetration of antibiotics, including tetracycline, erythromycin, and cefalexin sulfanilamidov in the mucous membrane of bronchus and lung tissue.

Dosing and Administration

Inside (regardless of meals), adults and children over 14 years in the 8-16 mg (c.logki 2-4), 3 times a day, children between 6 and 14 years in the 4-8 mg (1-2 c.logki) three times a day; children from 2 to 6 years in the 2-4 mg (1/2-1 c.lojka) three times a day for children up to 2 years to 2 mg (1 / 2 c.logki) three times a day. The course of treatment is from 4 to 28 days. The treatment is recommended to use enough liquid.

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