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BronhosanSee also BromhexineRoman nameBronchosan #The composition and the form of100 ml drops reception inside and inhalations contain bromgexina hydrochloride 80 mg, oregano 15 mg, oils produce 7.5 mg, anisovogo oil 2.5 mg, sweet oil mild 2.5 mg, peppermint oil Pepper 2.5 mg, eucalyptus oil 2.5 mg; Patients in dark glasses to 25 ml, in the box one bottle. Other ingredients : sucrose, digidrogenfosfat potassium, sodium digidrogenfosfat, polisorbit, ethanol, triglikol.Of drugsMukoliticescoe, skin, protivokashlevoe. Decreases viscosity and liquefaction to Bronchus secret from the activation of acid hydrolysis and sulfatirovannah glikoproteinov; Increased activity mertzatelnogo membrane facilitates transport patients, stimulates the secretion surfaktanta (in force in the cells Clara) and secretornuu activity bronchitis and salivary glands.PharmacokineticsThe ingestion drawn almost entirely, C_max plasma achieved through 1hr The first passage through the liver 80% metabolised (by conjugation). Associated with the plasma proteins (99%). T_1/2 - 4-5 h, the relative T_1/2 (with on / in the introduction), 12 h (from the back diffusion of tissue). Report mostly kidneys; 24 hours (after one reception) with urine output 35%, with the spread is 15%.IndicationsDiseases of the respiratory tract, causing education trudnootdelemy Bronchus secret (traheobronhit, obstruguy chronic bronchitis, emphysema lungs, bronhoektatical disease, bronchial asthma, disorders, cystic fibrosis, etc.). History after diagnostic and surgical interventions on the respiratory passages.Pregnancy and lactationContraindicated in the first trimester of pregnancy. At the time of treatment should stop breastfeeding.ContraindicationsHypersensitivity, saying disease stomach and duodenal ulcer in the process of being increased, jeluderne haemorrhage, pregnancy (I term), breast-feeding.Side-EffectsDiarrhoeal phenomenon forming increase in the concentration of whey transaminaz, allergic reactions (erythema, swelling of the skin and mucous membranes).Specific guidanceMukoliticescoe effect increases with the use of large quantities of fluid.Patient interactionImproves diffusion antibiotics and sulfanilamidov bronhialny in secret.PrecautionsNot recommended combined with the appointment of zefalosporinovmi antibiotics and drugs oppressive kashleva Centre (possibly build mucus in the respiratory passages). If bronchoobstructive syndrome before inhalation desirable bronholitika reception, and the children - a posture drainage and vibration massage chest.Dosing and AdministrationInside (in a small volume of a liquid or a piece of sugar) to 20 drops (children from 2 to 6 years to 10 drops, age 2 years, 5 drops) four times a day. Patients with renal insufficiency reduce single dose or increase the interval between приемами.Ингаляционн�� (diluted with distilled water in a ratio of 1:1 and heated to a temperature of the body) to 4 ml per 1 ingalatia (children over 10 years old-2 ml, from 6 to 10 years - to 1 ml, from 2 to 6 years to 10 drops, under 2 years, 5 drops), 2 times a day.Storage conditionsDrops for reception inside and d / ingal. : In dry the dark place at a temperature of 10-25 ° CShelf lifeDrops for reception inside and d / ingal. : 2 grams. |
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