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Carbocisteine

Chemical name

S-(Карбоксиметил)цисте ин

Gross

C5-H9-N-O4-S

Of drugs

The drugs-mukoliticescoe, soothing. Effect of activated sialova transferaza-enzyme bokalovidnykh cells mucous membrane bronchi. Normalizes quantitative ratio acidic and neutral sialomuzinov Bronchus secret (reduces the amount of neutral glikopeptidov increases the number gidroksisialoglikopeptidov), the suspension of the viscosity and elasticity of mucus. Is regeneration mucous membranes normalizes its structure, reducyruet bokalovidnykh number of cells, especially in the terminal bronchitis and, as a result, reduces mucus out. Restores secretion immunologicaki active IgA (specific protection), improves mukotiliarnyi Cl. The maximum level in the serum and mucosal lining the respiratory tract is achieved through two hours after taking into and stored in damp skin for 8 hours Treated biotransformation. T_1/2-3 h 15 min. Full withdrawal takes place through three days mostly in the urine, partly in an unmodified form, partly in the form of metabolites.

Indications

Diseases of the respiratory system with abundant and readily bronhialnam otdelemam, inflammatory diseases of middle ear and sinusal nose; A patient to ischemic or bronhografii.

Contraindications

Hypersensitivity, ulcerated stomach defeat, the violation of the kidney, acute glomerulonefrit, anesthetic, pregnancy and breast-feeding.

Side-Effects

Nausea, vomiting, pain in epigastria, diarrhoea, jeludern-kisherne bleeding, allergic reactions (skin rashes, swelling angioneuroticeski Kwinke).

Specific guidance

It should be borne in mind that one st.lojka carbozisteina of syrup contains 6 grams of sugar.

Patient interaction

Increases efficiency glukokortikoidna (mutually), and antimicrobial therapy of inflammatory diseases of the upper and lower respiratory tract. Potenziruet bronholiticeski theofillina effect. Carbozisteina activity weakened protivokashleve and atropinopodobne funds.

Dosing and Administration

Inside. Adults - 2 caps. or 15 ml (3 c.logki) 5% syrup three times a day; with the improvement on the one caps. or 10 ml (2 c.logki) 5% syrup three times a day. Children between 2 and 5 years 2.5-5 ml (1/2-1 c.lojka) 2.5% syrup four times a day, from 5 to 12 years, 10 ml of 2.5% syrup (2 c.logki) 4 times a day.

See also

All products of this group