Uric dobesilate

Chemical name

Calzieva salt 2,5-дигидроксибензолсу льфоновой acid

Gross

C12-H10-Ca-O10-S2

Characteristics

White or white with kremovatam or bi gigroskopicny white crystalline powder odourless. Easily soluble in water, soluble in 95% ethanol.

Of drugs

The drugs-antiagregatine, angioproteguoe. The slowly absorbed in the intestine, C_max in blood after taking into won at 5-6 h not to cross the GEB, excreted mainly kidneys within 24 hours Normalizes broken arteriol permeability and capillary increases their resistance increases the elasticity of cells, improves drainage and the lymph vessels increased leukocyte function (including antiauxidantnuu), moderately reduces agregatia platelets and blood viscosity has antigemorragicescoe effect.

Indications

Mikroangiopatii diabetic retinopathy and, trophic ulcers, glomeroelskleros, proper receptacles lower limbs, varicose expansion and flebita superficial veins, gemorroy, violations hemodynamics arteriovenoznogo origin stagnation peripheral oedema, circulation disorders, steroidnyi vasculit, bronchial asthma (gormonozawisimaya).

Contraindications

Hypersensitivity, bleeding (in the face of anti-admission), pregnancy.

Side-Effects

In rare cases, diarrhoea disorders, allergic reactions (skin rash).

Dosing and Administration

Inside, during or after meals, for 0.25 g 3-4 times per day or 0.5 g of 1-2 times a day during delivery within 2-3 weeks, and then reduce the dose to 0.25 g / sut. When treating retinopathy and mikroangiopatii appoint 0.25 g 2-3 times per day for 4-6 months, then 0.25 g / sut.

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