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Diovenor 600See also DiosminRoman nameDiovenor 600The composition and the form of1 tablet coated liner diosmina contains 600 mg, and auxiliary substances (микрокристаллическа�� cellulose, talc, silicon dioxide, stearic acid, gidroksipropilmetilzelluloza, titanium dioxide, oxides of red iron propilenglikol, poliauxietilenglikola stearate, �олиоксиэтиленгликол�� 6000, aluminevy lacquer red koshenili, carbon black iron); in a contour acheikova packing 15 pcs. , in a cardboard bundle two packaging.PharmacokineticsRapidly absorbed from the digestive tract. There are plasma from the second hours after admission, C_max plasma achieved in 5 hours Distributed and stored in the hollow walls of veins and subcutaneous veins of lower limbs, to a lesser extent, in the kidneys, liver and lungs, in other tissues in a few. Selective accumulation diosmina and / or its metabolites in venous blood reaches to nine hours after admission and continued for the next 96 hours Return with urine-79%, with spread-11% and jelchew 2.4%.IndicationsChronic venous insufficiency of the lower limbs, emerging sense of heaviness in the legs, pain and trophic disorders; Gemorroy (symptomatic treatment in the acute stage); Increased capillary permeability.Pregnancy and lactationCurrently in clinical practice does not establish any negative influence of the drug on the course of pregnancy and the development of a fetus. If necessary appointments while breastfeeding should abandon breast-feeding (no data on the penetration of the drug in breast milk). Experimental studies on animals have not identified tertogennogo effect.ContraindicationsГиперчувствительност ь.Side-EffectsDiarrhoeal phenomenon headache pain (in rare cases requiring a suspension of the treatment).Specific guidanceIf the gemorroidalnom krize should continue the therapy (a short course). In the absence of rapid clinical effect there is a need to undertake further study and adjust the therapy. There is evidence of a possible drug for the prevention of bleeding arising from the application of intrauterine device and the flebaektomii.Patient interactionClinically significant effects interaction with other LAN is available.OverdosingCases of drug overdose Diovenor 600 not described.Storage conditionsList B. The temperature is not above 25 ° CShelf life2The registration010,560 (ERP) |
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