Kurantil 25

Roman name

Curantyl 25

Characteristics

Derived pirimidina.

Pharmacokinetics

Rapidly absorbed from the stomach (most), and thin hair (few). Almost entirely associated with plasma proteins. C_max-within 1 h after administration. There is, first and foremost, in the heart and erythrocytes. Metabolized by the liver, bonding with glukuronova acid appears to jelchew of monoglukuronida. For T_1/2 tablets of 10 ± 2.2 h

Farmakodinamika

Lowers resistance to the coronary arteries at the level of small arms and arteriol increases the number kollaterley and kollateralny bloodstream; Improves concentration adenosine and ATP synthesis in miocarde improves his airway, reduces round, lowers AD agregatia inhibits platelets (improves, warns coronary arteritis), normalizes venous outflow; Reduces resistance brain receptacles corrigiruet placental blood; with the threat of pre-eclampsia warns dystrophic changes in platzente eliminates tissue hypoxia fruit to the accumulation of glycogen; provides modulation effect on the functional activity of interferon enhances nespecificescuu protivovirusnuu resistance to viral infections.

Indications

Treatment and prevention of cerebral circulation, discirkulatornaya encephalopathy, preventing arterial and venous trombozov and their complications, tromboamboliy after operation prosthetic heart valves platzentarna insufficient to risk pregnancies as part of the integrated therapy for any violations circulation, as an interferon inducer immunomodulator and for the prevention and treatment of influenza, Missouri.

Pregnancy and lactation

Perhaps supervised by a doctor and witnesses.

Contraindications

Hypersensitivity, acute myocardial infarction, unstable stenocardia, stenoziruty arteriosclerosis coronary arteries, asthma heart failure, subaortalny stenoses rivers, gipotenzia (severe), collapsed Already, saying disease stomach and duodenal ulcers (under increasing), bloody diates age to 12 years.

Side-Effects

It is rarely possible nausea, vomiting, diarrhea, dizziness, headache, mialgia; Gipotenzia, passing hyperemia of tachycardia; Allergic skin reaction.

Patient interaction

Weakening effect xantina derivatives (such as caffeine); - Increased indirect oral anticoagulants or acetylsalicylic acid. Increases gipotenzivne the antigipertenziveh funds weakens holinergicakie properties cholinesterase inhibitors.

Precautions

Avoid the use of natural coffee and tea (possibly weakening effect).

Storage conditions

List B. In the dark place at room temperature

Shelf life

5 years

The registration

008698

Literature

1. Ezra Y. et al. : Therapy and Prevention of Thrombotic Thrombocytopenic Purpurea During Pregnancy; American J. of Hematology. 51 (1) : 1-6, 1996 Jan.2. Hirose S. et al. : The Effect of Nifedipine and Dipyridamole on the Dopler Blood Flow Waveforms of Umbilical and Uterine Arteries in Hypertensive Pregnant Women. Asia Oceania J. ObstetricsGynecology of. 18 (2) : 187-93, 1992 June.3. Rogov VA , etc. : Azetilsalicilovaya acid kurantil and in the prevention of complications of pregnancy when glomerulonefrite and hypertensive disease. Therapy archive. 65 (6) : 65-8, 1993.4. Uzan S. et al. : Idiopatic Recurrent Fetal Growth Retardation and Aspirindipyridamole Therapy. American J. of Obstetrics and Gynecology. 160 (3) : 763-4, 1989 Mar.

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