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Kurantil n 25

Roman name

Curantyl N # 25

The composition and the form of

1 tablet contains dipiridamola 25, or 75 mg; in glass bottles of 100 pcs. , in box 1 orange (25 mg), or blistere 20 pcs. , in box 2 blisters (75 mg) .1 tablet coated bullets, 25 or 75 mg; in glass bottles of 120 pcs. , in a Box 1 orange (25 mg), or blistere 20 pcs. , in box 2 blisters (75 mg).

Characteristics

Beans : 4.2.2, from yellow to zelenovato-jeltogo Tsveta.tabletki Film-coated : ploskotsylindriceskie 218 , yellow.

Of drugs

Antiagregatine, angioproteguoe, immunomodulirutee. Competitive ingibiruet adenozindezaminazou, contributing to the accumula 218 tion of adenosine involved in the regulation of coronary blood flow, as well as the ability of platelets to aggregation and adhesion. Does fosfodiesterzu and increases in the cells Zamf. As derivative pirimidina, Kurantil is interf 218 eron inducer and provides modulation effect on the functional activity of interferon; Increases nespecificescuu protivovirusnuu resistance to viral infections.

Pharmacokinetics

Rapidly absorbed from the stomach (most), and thin hair (few). Almost entirely associated with plasma proteins. C_max-within 1 h after administration. T_1/2 - 20-30 minutes. There is, first and foremost, in the heart and erythrocytes. Metabolized by the liver, bonding with glukuronova acid appears to jelchew of monoglukuronida.

Farmakodinamika

Lowers resistance to the coronary arteries at the level of small arms and arteriol increases the number kollaterley and kollateralny bloodstream; Improves concentration adenosine and ATP synthesis in miocarde improves his airway, reduces round, lowers AD agregatia inhibits platelets (improves, warns coronary arteritis), normalizes venous outflow; Reduces re 218 sistance brain receptacles corrigiruet placental blood; with the threat of pre-eclampsia warns dystrophic changes in platzente eliminates tissue hypoxia fruit to the accumulation of glycogen; provides modulation effect on the functional activity of interferon enhances nespecificescuu protivovirusnuu resistance to viral infections.

Indications

Treatment and prevention of cerebral circulation, discirkulatornaya encephalopathy, preventing arterial and venous trombozov and their c 648 omplications, tromboamboliy after operation prosthetic heart valves platzentarna insufficient to risk pregnancies as part of the integrated therapy for any violations circulation, as an interferon inducer immunomodulator and for the prevention and treatment of influenza, Missouri.

Pregnancy and lactation

Perhaps supervised by a doctor and witnesses.

Contraindications

Hypersensitivity, acute myocardial infarction, unstable stenocardia, stenoziruty arteriosclerosis coronary arteries, asthma heart failure, subaortalny stenoses rivers, gipotenzia (severe), collapsed Already, the propensity to bleeding (hospital disease stomach and duodenal ulcer, etc.), bloody diates age to 12 years.

Side-Effects

It is rarely possible nausea, vomiting, diarrhea, dizziness, headache, mialgia; Gipotenzia, passing hyperemia of tachycardia; Allergic skin reaction.

Patient interaction

Weakening effect xantina derivatives (such as caffeine); - Increased indirect oral anticoagulants or acetylsalicylic acid. Increases gipotenzivne the antigipertenziveh funds weakens antiholinergicakie properties cholinesterase inhibitors.

Precautions

Avoid the use of natural coffee and tea (possibly weakening effect).

Dosing and Administration

Inside, erh, not liquid, squeezed small amounts of liquid. In order to reduce the aggregate count : 75-225 mg / day in a number of techniques, in severe cases, dose increase to 600 mg / Sut.dla preventing influenza a 218 nd other scientists, especially during epidemics : 50 mg / day (Table 2. Or 2 tablets of 25 mg once), once a week for 4-5 Ned.dla relapse prevention, they frequently respiratory viral infections patients : 100 mg per day as follows : 50 mg (2 table. or two tablets of 25 mg) twice a day with an interval of two hours, once a week for 10 weeks.