Nicotinic acid

Chemical name

3-piridincarbonova acid

Gross

C6-H5-N-O3

Characteristics

The white crystalline powder and odourless, slabokislogo taste. It is soluble in cold water (1:70), to the hot (1:15), not soluble in ethanol, it is very little in the air.

Of drugs

Drugs, the lack of complementary vitamin PP (specify), sossoudorasshiratee, gipolipidemicescoe, гипохолестеринемичес кое. Included in the group prosteticescuu enzymes which carry hydrogen : никотинамидадениндин уклеотида (AND) and �икотинамидадениндин��клеотидфосфата (NADF) regulates �кислительно-восстано вительные processes fabric respiration, synthesis of proteins and fats, the disintegration Glikogena.ugnetet lipolysis in adipose tissue, reduces the synthesis LPONP. Chelsea normalizes blood : reduces total cholesterol, engineers, triglycerides and increased LPVP has antiaterogennami properties. Provides sossoudorasshiratee action including receptacle brain, improves increases fibrinoliticescuu activity of the blood and reduces agregatia platelets (reduces tromboksana A_2). Promotes transition trans-forma retinol in tsis-formu used in the synthesis of rodopsina. Is gistamina released from the depot, and the activation of Kininov.obladaet detoxification properties. Is effective in disease-Hartnupa genetically from the exchange (intake and tissues) triptofana, with a deficit of synthesis Kislota.horosho nicotine absorbed in the department piloricescom stomach and the upper gastrointestinal divisions bowel. Partly biotransformiroetsa in liver education N-metilnikotinamida, metilpiridoncarboksamidov, glukuronida and complex with glitzinom. Return with urine, mostly unaltered.

Indications

Профилактика и лечение пеллагры (авитаминоз PP); атеросклероз, гиперлипидемия (в т.ч. гиперхолестеринемия, гипертриглицеридемия), спазм периферических сосудов, в т.ч.Prophylaxis and treatment