Pentoksifillin-akri

Roman name

Pentoxifylline-Akri

The composition and the form of

Male Film-coated-1 tabl.pentoksifillin 0.1 gu contour acheikova packing 10 pcs. ; Bundle in a cardboard six packages.

Pharmacokinetics

Quickly and completely absorbed from the digestive tract. C_max noted after one hour after administration. After 8 h concentration decreased significantly (up to 10% of primary). Return with urine in the form of inactive metabolites.

Farmakodinamika

Decreases viscosity of the blood, improves its flow properties. Provides sossoudorasshiratee little effect, several reduces round, the positive inotrope effect.

Indications

Violation of peripheral blood and cord blood as a result of atherosclerosis, ischemic cerebral stroke discirkulatornaya encephalopathy, trophic of tissues and organs (coronary arteries or veins, varicose veins frostbite), diabetic angiopatia, paresthesia, Reynaud disease, the acute occlusion of central retinal artery, the internal ear vascular genesis; also applies in patients with artificial heart valves and in the aftermath of Operation bypass arteries.

Pregnancy and lactation

Contraindicated.

Contraindications

Hypersensitivity, acute myocardial infarction, massive bleeding, bleeding in his eye, a simple and diabetic proliferirutaya diabetic retinopathy expressed ateroskleroticescoe defeated cerebrovascular disease and heart disease, heavy human heart rhythm.

Side-Effects

Nausea, vomiting, dizziness, headache, nervousness, drowsiness / insomnia, diarrhoea phenomenon tachycardia, changing body weight, swelling, bleeding, hyperemia skin, increased fractures nails, skin allergic reactions.

Specific guidance

The treatment should be regularly measured AD. When coupled with a antikoagulyantami there is a need to control the performance of blood coagulation.

Patient interaction

Do gipotenziveh effects of insulin, oral protivodiabeticakih drugs.

Dosing and Administration

Inside, the food with liquid, squeezed water. Initial dose for 0.2 g three times a day. With the improvement of the daily dose can be reduced to 0.1 grams per 3 admission. The course of treatment is 2-4 weeks. The easiest forms of the disease - 0.2 g / sut. Patients with Cl creatinine less than 10 ml / min designate 50-70% of the recommended dose.

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