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Pentoksifillin reeveSee also PentoxifyllineRoman namePentoxifylline RIVOThe composition and the form of1 tablet covered kishechnorastvorima liner pentoksifillina contains 100 mg; in a carton 6 blisters to 10 st.1 tablet retard covered kishechnorastvorima liner-400 mg; in a carton 2 blisters to 10 pcs.Of drugsSossoudorasshiratee, antiagregatine, improves microcirculation. Does adenozinove receptors ingibiruet fosfodiesterzu facilitates Zamf accumulation in the cells.PharmacokineticsThe ingestion quickly and completely absorbed, C_max pentoksifillina and its metabolites is 2-4 hour sustained remains in the blood for 12 hoursFarmakodinamikaImproves microcirculation and the flow properties of blood vessels expand, improves supply tissue oxygen, reduces agregatia count increases elasticity cells, reduces the viscosity of blood.IndicationsAterosklerotical and discirkulatornaya encephalopathy, cerebral ischemic stroke of peripheral blood circulation due to atherosclerosis, diabetes, pneumonia, diabetic angiopatia, obliteriruty endarteriit, nutritional disorders (postflebitny syndrome, trophic ulcers, gangrene stomach), angioneiropatia (parestesia illness Reynaud), the lack of retinal blood and mucous membrane eye of the inner ear, accompanied by tugouhostew.ContraindicationsHypersensitivity, acute myocardial infarction, massive bleeding, bleeding in the brain, bleeding in the retina eye pregnancy.Side-EffectsNausea, vomiting, a feeling of gravity in epigastria, diarrhoea; Headache, dizziness, tachycardia, hyperemia of stenocardia, arterial hypotension, bleeding from splashing out skin and mucous membranes, skin rashes, itching, urticaria.PrecautionsDuring treatment should monitor the AD. Be wary combine with hypotensive means antidiabeticakimi oral medications, insulin, antikoagulyantami.Dosing and AdministrationInside, with liquid squeezed more water to 100-500 mg three times a day.Storage conditionsтабл.п.о.раствор./кише��н. : List B. In the dark place at a temperature of 15-25 °Cтабл.п.о.раствор./киш ечн.ретард : List B. In the dark place at a temperature of 15-25 ° CShelf lifeтабл.п.о.раствор./кише��н. : 3 г.табл.п.о.раствор./киш ечн.ретард : 3 and |
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