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Propanorm

See also Propafenone

Roman name

Propanorm

The composition and the form of

1 tablet coated liner contains propafenon hydrochloride 150 mg, in a contour acheikova packing 10 pcs. , in a carton five packages.

Of drugs

Antiaritmicescoe. Does beta-adrainoretseptora and rapid sodium channels.

Farmakodinamika

Refers to IC Class complications funds. Dozozawisimo reduces the depolarization, inhibits 0 phase of the building. The blockade sodium channel increases with the numerical (castotnozawisimaya blockade). Wrinkles on the lift Guisa and Purkinje fibers, lengthens and broadens the range of Micro reinspection PQ, AH (auricle-beam Guisa) and HV (beam-Guisa encyclopedia). Increases effective refrakterny period predserdiah, AV node, additional bundles and jeludockah (to a lesser extent).

Indications

Already Mertzatelnaya (mild paroxizmov and relapse prevention), retidivirutaya najeludochkovaya tachycardia (including the Wpw-sindrome), ventricular arrythmia, предсердно-желудочко��ая on the "re-entry" tachycardia.

Pregnancy and lactation

Contraindicated. At the time of treatment should stop breastfeeding.

Contraindications

Chronic heart failure III functional class (NYHA on), aetiology, symptoms of weakness sunusnogo unit of conductivity (sinoatriale, AV and intraventrikuliarnae) cardiogenny shock arterial gipotenzia, chronic obstructive lung diseases, infants, pregnancy, breast-feeding.

Side-Effects

For part of the stomach : the appetite, the bitter taste and a sense of numbness in the mouth, nausea, Rvota.so the nervous system and sensory organs : dizziness, headache, anxiety, insomnia and Zrenia.prochie : ortostatical gipotenzia.

Specific guidance

With long-term use may change thresholds электрокардиостимуля тора (check the man's heart rhythm and resubmit its program).

Precautions

The expansion of Micro more than 20% or extension QT interval dose should be reduced in progressirovanii violations, the preparation lift to the normalization of the ECG.

Dosing and Administration

Inside. Dose picked individually under medical supervision, control and measurement AD; Usually 150 mg 2-3 times a day, the optimal daily dose of 450-mg; If necessary, until 900-1200 mg / sut.

Storage conditions

tabl.p.o. : List B. In dry the dark place at a temperature of 15-25 ° C

Shelf life

tabl.p.o. : 4 g.

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