Directory Organotropona funds Cardiovascular funds Blockers calcium channel
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Blockers calcium channel

The group

Ions play an important role in the regulation of various processes of life organism. Entered into cells, they trigger atherosclerosis processes (making ATF Zamf, Tiofat proteins, etc.), for the physiological functions of cells. In high concentrations (including the Ischemia, hypoxia and other pathological conditions), they can be overly processes cellular metabolism, increase the requirement tissues of oxygen and cause various destructive changes. Transmembranny transport calcium ions through special channels, which are macromolekularnae protein, peptide rassekate biosloi cell membranes. As their calziewami or "slow", the channels (as opposed to the "fast" channels through which transported other ions). Inside the flow of calcium ions through the membranes subject to a number of exogenous factors (acetylcholine, kateholamin, serotonin, histamine, etc.), or membrane potential.
In the late 1960s, was discovered ability of some exogenous substances hinder the passage of calcium ions through the "slow" channels (prenilamin, verapamil). Currently, the number of known compounds that have a similar effect. They unite under the group name blockers, calcium channel (antagonists calcium ions). The chemical structure they represent fenilalkilamin (verapamil, gallopamil, etc.), 1,4-digidropiridina (nifedipin, nitrendipin, amlodipin, nikardeepin, etc.) benzotiazepina (diltiazem, etc.), etc. (zinnarizin, flunarizin). Some of these drugs from different pharmacological groups have the ability moderately affect the current calcium inside cells (phenytoin, propranolol, indometacin). Spectrum pharmacological activity of calcium antagonists include effects on airway diseases, activity sinusnogo hub, AV conduction, tone receptacles and vascular resistance, the bronchi, the gastrointestinal tract and urinary tract. These drugs have the potential to inhibit agregatia platelets and simulate the neiromediatorov of presinapticakih suffixes. The antagonists of calcium ions due to their impact on the cardiovascular system. Calling the receptacles and reducing round, they dismissed AD improve coronary blood and oxygen reducyruut query tool. These drugs lower proportion AD dose, the therapeutic dose would not significantly affect the normal AD, are orthostatic phenomena. Drugs of this group, affecting anxiety conductivity and cardiac muscles are used as a means of complications. Merit calcium antagonists is the lack of adverse effects on London exchange, elektrolitny balance and tolerance to carbohydrates. Verapamil, nifedipin, diltiazem is the short duration of action necessitated 3-4 multiple stages during the day and accompanied by fluctuations vazodilatirutego and gipotenzivnogo effect. Medicines with a slow release drug ingredients provide continuity therapeutic concentration and increase the duration of the preparation.
A calcium antagonists (mostly digidropiridina) different vsokospecificski impact on the individual organs and vascular regions (eg nimodipin to think receptacles).

Drugs

  • Amlodipine
  • Bepridil
  • Diltiazem
  • Diumancal
  • Felodipine
  • Fendiline
  • Flunarizine
  • Gallopamil
  • Isradipine
  • Lacidipine
  • Mibefradil
  • Nicardipine
  • Nifedipine
  • Nitrendipine
  • Riodipine
  • Verapamil
  • Agen
  • Adalat
  • Adalat n
  • Akrydipin
  • Aldizem
  • Altiazem pp
  • Amlovas
  • Amlodil
  • Amlodipina besilat
  • Anifed
  • Ankardin
  • Apo-diltiaz
  • Auronal
  • Atsupamil
  • Bepricor
  • Blokaltsin
  • Blokaltsin 90 retard
  • Verkard
  • Veramil
  • Verapabene
  • Verapamil (mival)
  • Verapamil retard
  • Verapamil, alkaloid
  • Verapamil-ratiofarm
  • Verapamila hydrochloride
  • Verapamila hydrochloride 0.08 g
  • Verapamila hydrochloride injection 0.25%
  • Vero-amlodipin
  • Vero-verapamil
  • Vero-nifedeepin
  • Verogalid ES 240 mg
  • Veromil
  • Gerbesser
  • Gipernal
  • Gipernal 10
  • Gipernal 5
  • Gipernal drops
  • Danistol
  • Depin-e
  • Diazem
  • Diacordin 120 retard
  • Diacordin 60
  • Diacordin 90 retard
  • Dilacor xr
  • Diljina
  • Dilzem
  • Dilkardia
  • Diltazem avg
  • Diltazem-60
  • Diltiazem gexal retard
  • Diltiazem hydrochloride
  • Diltiazem lannaher
  • Diltiazem nikomed
  • Diltiazem retard
  • Diltiazem avg
  • Diltiazem, pliva sa
  • Diltiazem-60
  • Diltiazem-ratiofarm
  • Dilren
  • Dilzem
  • Diomankal
  • Diomankala pills 0.01g
  • Zenusin
  • Silden
  • Izoptin
  • Izoptin sr 240
  • Izoptin avg
  • Kalcek
  • Calzigard retard
  • Calzigard-10
  • Calzigard-5
  • Kardil
  • Cardilopin
  • Karin-fer
  • Corvadil
  • Kordafen
  • Kordaflex
  • Kordipin
  • Kordipin xl
  • Kordipin retard
  • Korinfar retard
  • Korinfar Uno
  • Korinfar, awd
  • Kortiazem
  • Latipil
  • Lecoptin
  • Logimax
  • Lomir
  • La Lomir
  • Lyusopress
  • Miogard
  • Nerdeepin
  • Nikardia
  • Nikardia tilt retard
  • Nitrendipin
  • Nifadil
  • Nifebene
  • Nifegexal
  • Nifedex
  • Nifedicap
  • Nifedikor
  • Nifedipat-5, 10
  • Nifedipat-retard
  • Nifedipin 20 retard
  • Nifedipin, pliva sa
  • Nifedipin-icn
  • Nifedipin-mik
  • Nifedipin-n.s.
  • Nifedipin-ratiofarm
  • Nifedipin-farkos
  • Nifedipin-fpo
  • Nifecard
  • Nifecard hl
  • Nifelat
  • Nificard
  • Novo-nifedin
  • Norwadin
  • Norvasc
  • Normodipin
  • Oktidipin
  • Omelar gym
  • Osmo-adalat
  • Plendil
  • Pozikor
  • Ronian
  • Senzit
  • Sibelium
  • Sponif 10
  • Stamlo
  • Tenox
  • Tiakem
  • Unipres
  • Falicard
  • Long Falicard
  • Felodip
  • Fenamon
  • Fenigidin
  • Fenigidina pills 0.01g
  • Finoptin
  • Flamon
  • Flecor-n
  • Foridon
  • Fauridona injection 0.01%
  • Fauridona pills 0.01g
  • Ekodipin
  • Etizem