Berlipril 5

Roman name

Berlipril # 5

The composition and the form of

1 tablet (Berlipril 5) contains englaprila maleate 5 mg; blistere in 10 pcs. , in box 3 blister.1 tablet (Berlipril 10), 10 mg; blistere in 10 pcs. , in box 3, 5 or 10 blisterov.1 tablet (Berlipril 20), 20 mg; blistere in 10 pcs. , in box 3 5 or 10 blisters.

Of drugs

Antihypertensive, sossoudorasshiratee. Ingibiruet agents and as a result reduces the education of angiotenzina I angiotenzina II, eliminating thus sossoudossouerveshchee the latter. Impact round, reduces pre - and the postnagruzku miocard. Reduces pressure predserdii law and the terms of a small blood.

Indications

Essential hypertension, heart failure (in combination with cardiac glycosides and / or dioretikami).

Pregnancy and lactation

Contraindicated.

Contraindications

Hypersensitivity, swelling angioneuroticeski in history, the primary giperaldosteronizm, stenoses renal artery stenoses aortalni or mitral valve gipertrofica cardiomyopathy, liver disease and kidney perezajennaya kidney, dialysis, kollagenozy, child.

Side-Effects

Diarrhoeal disorders, a change of taste and hypotension, violations Orthostatic regulation, zagrudinnaya pain, arrhythmia, tachycardia, myocardial infarction, cerebral stroke, dizziness, headache, weakness, sputannosti consciousness, anxiety, insomnia, giperkaliemia, flebita violation of the kidney and / or liver, hepatitis, cough reflex, changing picture blood disorders, hearing and vision sinkope, exfoliativei dermatitis, syndrome Stevens-Johnson, photosensitization, angioneuroticeski swelling.

Patient interaction

The effect of declining NPVS and more narkoznami drugs. Immunosuppressants, allopurinol, cytostatics, corticosteroids gematotoksicnosti added. Together with the use of cyanide, kalisberegatmi dioretikami, geparinom giperkaliemia possible. Do the alcohol and increases the concentration of lithium in the plasma.

Dosing and Administration

Inside, regardless of the meal, with arterial hypertension (monotherapy) : initial dose of 5 mg once a day (1 tab. Berlipril 5 1 / 2 table. Berlipril 10, or 1 / 4 table. Berlipril 20); in the absence of the effect in 1-2 weeks dose increase to 5 mg (after the initial dose patients to be under medical supervision for at least 3 hours before stabilizing AD). If necessary, and good endurance dose increase to 40 mg / day in the reception 1-2; In a couple of weeks are in the process of supporting dose of 10-40 mg / day for 1-2 reception. In moderate hypertension : average daily intake of 10 mg. The maximum daily dose of 40 mg. With simultaneous treatment dioretikami in giponatriemii (concentration of sodium ions in the serum less than 130 mmol / l), or the concentration of creatinine in the serum more than 0.14 mmol / l initial dose of 2.5 mg once a day. In renovskularna hypertension : primary dose-2.5-5 mg / day; Maximum daily dose of 20 mg. In chronic heart failure : initial dose of 2.5 mg once, with a gradual increase of 2.5-5 mg every 3-4 days, in accordance with the clinical response to the over doses, depending on the size of the AD, but not more than 40 mg / day one or two reception. Sad to less than 110 mm Hg and the older patients initial dose - 1.25 mg; dose selection is normally held in the next 2-4 weeks; mean supporting dose-5-20 mg / day 1-2 reception. In bessimptomnom violation of the left heart : 2.5 mg twice a day, then dose (up to 20 mg / day in 2 admission) picked up in the light of Time. In chronic renal failure : when Cl creatinine 80-30 ml / min, 5-10 mg / day, 30-10 ml / min, 2.5-5 mg / day, less than 10 ml / min, 1,25-2,5 mg / day only in the days of dialysis. When too expressed AD lower dose gradually reduced.

Storage conditions

table. : List B. In dry the dark place at a temperature of no higher than 25 ° C

Shelf life

table. : 3 and

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