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Monopril

See also Fosinopril

Roman name

Monopril

Indications

Arterial hypertension (whether in the form alone or in combination with other antigipertenzivei drugs, in particular with tiazidnami dioretikami). Heart failure (in combination with dioretikami).

Pregnancy and lactation

Contraindicated in pregnancy. The ACE inhibitors for the II and III trimester of pregnancy to cause damage or loss of the developing foetus. Since Monopril found in breast milk, the drug should not be used during breast-feeding.

Contraindications

Гиперчувствительност ь (including angioneuroticeski swelling for other ACE inhibitors in history), pregnancy, the period of breastfeeding. Safety and effectiveness of the children has not been established.

Side-Effects

Generally, side effects, as the young and old patients are easy and temporary. Most are : dizziness, coughing, rapid heartbeat, zagrudinne pain, skin, skin, muscle pain, parestesia, feeling fatigue, the palate and other types of sensitivity, nausea, vomiting, neuralgia.

Specific guidance

Before treatment is required at earlier antigipertenzivnuu therapy, the extent of the investigations, no salt and / or liquid, and other clinical circumstances. If possible, should repeal all previously assigned antigipertenzivnuu therapy, a few days before the start of treatment Monoprilom.snijenia doses patients with compromised renal function and liver Trebuyutza.razlici not to the efficacy and safety of drug treatment of elderly (65 years and older) and young people were not forthcoming. However, it can not be ruled more influenced patients older to препарату.Безопаснос��ь and the effectiveness of Monoprila in children has not been established.

Patient interaction

The combined application antatsidov (eg aluminium or magnesium hydroxide, simetikon) may reduce inflammatory drug Monopril, and the use of drugs to be at intervals of not less than 2 hours If you are applying ACE inhibitors with lithium salts, the concentration of lithium in the serum and the risk of lithium toxicity may be higher, so the Monopril and preparations should lithium with caution. Reported that indometacin may reduce antihypertensive activity other ACE inhibitors, particularly in patients with hypertension nizkoreninova. Other NPVS (eg aspirin) can have a similar effect. If you are applying to Monoprila dioretikami or in combination with a strict diet, limiting salt, or dialysis, can develop expressed gipotensus reaction, especially in the first hour after receiving the initial dose fosinoprila. In order to avoid the risk of a giperkaliemii Monopril while kalisberegatmi dioretikami (spironolactone, amiloride, triamteren, etc.) and kalisoderjasimi additives to the food should be approached with caution. Determining the concentration of potassium in serum from the patient to be at short intervals. Bioavailability drug while being subjected to hlortalidonom, nifedipinom, zimetidine, metoklopramidom, propantelinom, digoxinom, aspirin, varfarinom does not change. ACE inhibitors increase the antihypertensive drugs used for general anesthesia.

Storage conditions

B. List in a dry place at room temperature

Shelf life

3 years

The registration

012700/01-2001

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