Hydralazine

Chemical name

1(2Н)-Фталазинонгидраз��н (in the form of the grounds and monogidrohlorida)

Gross

C8-H8-N4

Characteristics

The white crystalline powder. Rat in the water in the ratio 4,4:100 little in alcohol.

Of drugs

The drugs-gipotenzivne, sossoudorasshiratee. Oppressing transport of calcium into cells miofibrill arteriol and / or free Wärmetauscher ions. Reducing AD by reflectorian increase muscle sympathetic nervous system, increasing heart discharge; Kidney increases bloodstream.

Indications

Arterial hypertension, hypertonic kriz, female heart failure with a high postnagruzka, eclampsia.

Contraindications

Hypersensitivity expressed arteriosclerosis arteries systemic lupus red and peripheral neuropathy.

Side-Effects

Headache, dizziness, fever and hypotension, tachycardia, cardialgia, stenocardia, tides, sweating, slezotechenie, nausea, vomiting, volchanochnopodobnyy syndrome.

Specific guidance

Since iron is painted complexes, which should be avoided ground water products or solutions with iron objects.

Precautions

Be wary appointed in coronary insufficiency.

Dosing and Administration

Inside, the food, starting with 10-25 mg 2-4 times a day with a gradual increase to 100 to 200 mg / day (4 admission). Higher doses : single 100 mg daily to 300 mg. Course 2-4 weeks; Second course in 3-5 months.

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