Chlortalidone

Chemical name

2-Хлор-5-(2,3-дигидро-1-ги��рокси-3-оксо-1Н-изоинд��л-1-ил)бензолсульфона��ид

Gross

C14-H11-Cl-N2-O4-S

Characteristics

White or white with weak yellowish sheen melkochristalliceski powder. Virtually nerastvorim water, little soluble in alcohol.

Of drugs

The drugs-dioreticescoe. Does reabsorbqiyu sodium, chlorine, potassium and bicarbonate distal channel has been little impact on the proximale. The delay glucose and uric acid. Rapidly absorbed from the digestive tract, a 90% binds to plasma proteins and cell. Write mainly faeces and urine. Mochegonny effect is 2-4 hours and lasts 72 hours

Indications

Essential hypertension, oedema and cardiac failure.

Contraindications

Violation of the liver and kidney failure, diabetes, gout, pregnancy.

Side-Effects

Weakness, nausea, vomiting, diarrhoea, gipokaliemia, gipohloremicski alkaloz, giperglikemia, giperuriquemia and dermatitis.

Patient interaction

Do effect gipotenziveh funds.

Dosing and Administration

Inside, in the morning-prandial 25-200 mg. The selection of the dose individually.

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