Clopamide

Chemical name

цис-3-(Аминосульфонил)- 4-хлор-N-(2,6-диметил-1-пи��еридинил)бензамид

Gross

C14-H20-Cl-N3-O3-S

Of drugs

The drugs-natriyureticescoe, dioreticescoe, protivooterne, gipotenzivne. Does enzyme of kidney cancer in the BGs hinges Genle, oppressing reabsorbqiyu sodium. Ingibiruya carboangidrazou in the proximal section izvitah channel to exacerbate secreta potassium carbonate and phosphate. Little impact on KHS. The amount of urine is a decrease of circulating blood and reduce systemic AD. It absorbed in the digestive tract. The action in a couple of hours with a maximum effect, through 6900, the duration of 15-16 hours

Indications

Otechny syndrome temperate and moderate symptoms (heart failure, portal hypertension, renal swelling genesis), arterial hypertension.

Restrictions on the use of

Breast-feeding, child age (safety and efficacy of the use of children to be determined).

Contraindications

Personally, liver failure, severe renal failure, arterial hypotension, Addison disease, gipokaliemia, giponatriemia, gipohloremia, uremia, гиперчувствительност ь sulfonamidam to.

Side-Effects

Diarrhoeal events (nausea, vomiting), irregular, arterial hypotension, muscle weakness, hyperemia skin, gipokaliemia, giperglikemia, giperuriquemia, allergic reactions.

Patient interaction

Do the gipotenziveh funds, the risk of cardiac toxicity glycosides. Reduces the gipoglikemicakih drugs.

Dosing and Administration

Inside. In oternm syndrome average dose of 20-40 mg (if necessary - 80 mg) one morning. In hypertension average dose-10 mg (20 mg) one morning after having a meal.

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