Yohimbine hydrochloride

Chemical name

Метил-(16альфа,17альфа)-1 7-гидроксийохимбан-16-к арбоксилат (as hydrochloride)

Gross

C21-H26-N2-O3.HCl

Characteristics

Produce a crust zapadno-africansky tree Corynanthe yohimbe and roots Rauwolfia serpentina. Crystalline powder odourless.

Of drugs

The drugs-enhancing erectilnuyu function, stimulating potency. Yes blocking central and peripheral presinapticalkie альфа_2-адренорецепто��ы. In high doses, has the ability to block postsinapticalkie альфа-адренорецептор��. Improves erectilnuyu function (presumably due to increased blood flow to the sexual organs and reduce outflow). Increases mood may exacerbate тревожность.Оказывае�� antidiureticescoe Effects (possibly through stimulation gipotalamicakih centres and the release of hormones in the back glands).

Indications

Psychogenic and functional impotence.

Restrictions on the use of

Violation of the cardiovascular system, saying the disease stomach and duodenal ulcers in history, the existence of mental illness.

Contraindications

Hypersensitivity expressed by the human kidney / liver, lability AD, uncontrolled gipo-/gipertenzia, simultaneous adrenomimetikov.

Side-Effects

Initiation, tremor, headache, dizziness, anxiety, irritability, increased AD tachycardia, ortostaticeski collapse (in high doses), strengthening motion activity, nausea, stomachache, vomiting, diarrhoea, priapizm, reducing diureza.

Patient interaction

It should not be combined with drugs that affect mood, including antidepressants.

Precautions

One of a host of diseases involving risk of a sudden collapse of the AD and tachycardia.

Dosing and Administration

Inside (at the time of delivery, squeezed drinking water) for 5-10 mg 1-3 times a day for 10 weeks (maximum). If necessary, repeat the course.

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