This page is translated automatically with a help of Google Translate
- Other antibiotics
- Macrolides and azalida
The groupAntibiotics-life products (or their synthetic analogues and homologues) living cells (bacterial, fungal, and the plant and animal origin) selectively suppress the functioning of other cells, microorganisms, tumor etc. This group includes hundreds of different products the chemical structure of different range and mechanism of action, side effects and indications for use. There are antibiotics with antibacterial, protivoprotosana, protivogribkova, antivirus and antitumor activity.
Antibiotics are divided into groups according usually with the chemical structure (beta-lactama, makrolida, aminoglikozida et al).
The high selectivity of antibiotics on microorganisms in their low toxicity, most likely linked to the characteristics of microbial metabolism of cells and the significant differences in the speed synthesis structural components of the macro-cells and micro-organisms. The use of antibiotics can develop resistance of microorganisms (especially rapidly towards streptomitino, oleandomitino, rifamitino, slow to penitsillinam, tetratziklinam, levomicetinu rarely to polimiksinam). The education of cross-resistance (that is not only used to the drug, but also to antibiotics similar structure, for example, all tetratziklinam).
In spite of the high selectivity of, antibiotics are a number of side effects : allergic reactions (including anaphylactic shock), superinfection (goiter, weakened immunity), and toxic phenomena (including dispepshiyu, flebita, human liver and kidneys, etc.).
The high activity and low toxicity makes it possible to use antibiotics as a means for the treatment of various infectious and malignant diseases.