Villprafen

Roman name

Wilprafen

The composition and the form of

1 tablet coated liner jozamitina contains 500 mg, in blistere 10 pcs. ; in a box blister.10 1 ml suspension for oral administration (1 cup graduated) contain jozamitina propionata 320.4 mg (jozamitina 300 mg), in vial dark glass 100 ml; in a box one bottle complete with thick graduirovannam (through 2.5 ml) stakanchikom 10 mle.10 ml suspension for oral administration Fort (1 cup graduated) contain jozamitina propionata 640.8 mg (jozamitina 600 mg), in 100 ml ml; in a box one bottle complete with thick graduirovannam (through 2.5 ml) stakanchikom 10 ml.

Farmakodinamika

Active against grampolaugitionah and gramotricationah bacteria, intracellular microorganisms.

Clinical pharmacology

Quickly and completely absorbed from the digestive tract. C_max achieved in 1-2 hours Connectivity plasma protein is 15%. Metabolised in the liver, excreted in jelchew and urine (less than 20%).

Indications

Infections (including hlamidiynye, mikoplazmenne and mixed), the respiratory tract and Lor-organov (pharyngitis, otitis average, sinusit, laringit, tonzillit and paratonzillit, acute bronchitis, pneumonia, including severe form; Skin and soft tissues (piodermia, furunkoulez, anthrax, rojistoe inflammation, acne, limphangit, lymphadenitis, venerica limfogranulema); Genitourinary system (medicine, prostate, chlamydia, mikoplazmoz, ureaplazmoz, gonorrhoea, syphilis); dental infections (gingivit, parodontit, odontogenne abscesses); diphtheria, scarlet fever, whooping cough, psittakoz.

Pregnancy and lactation

It may be shown.

Contraindications

Hypersensitivity, severe violations of the liver.

Patient interaction

Ters bakteritidnyi effect other antibiotics (penicillin, zefalosporin, linkomicin) contragestive effect of hormonal contraceptives, slows eliminatiu xantinov, digoxin, cyclosporine, preparations containing terfenadin or astemizol. The development of cross-resistance to other makrolidam.

Overdosing

Currently, the cases of drug overdose Villprafen were reported.

Precautions

The caution should be appointed in the face of kidney failure.

Dosing and Administration

Inside, the pill is not a liquid, squeezed small amounts of water, warm appoint between meals (content bottle vesbaltarve first) : 1-2 g / d or reception. Duration of treatment streptococcal infections of at least 10 days. To treat ordinary and teens ball on the 500 mg twice a day over a period of two to four weeks, followed by 500 mg once a day for eight Ned.novorozdennym and children under 14 years of age, 30 to 50 mg / kg / day in 3 admission.

Storage conditions

List B. The temperature is not above 25 ° C

Shelf life

3 years

The registration

012028/02

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