Directory Antimicrobials, and protivoparazitarnae protivoglistnae funds Antibiotics Monobactama
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Monobactama

The group

This group of antibiotics (aztreonam) is structurally different from other beta-laktamov lack of a molecule visualization with beta-laktamnam benzene ring. They operate mainly in aeroba gram. Vsokostabilna in the presence beta-laktamaz (penitsillinaz, zefalosporinaz, carbapenemaz). The antimicrobial activity linked to a specific compleksirovaniem with beta-laktamotropnami protein (пенициллинсвязывающ��й protein 3) cell wall leading to lizisu cells. Unlike other beta-laktamnah antibiotics, they do not cause cross allergization; Last significantly limits the use penitsillinov, zefalosporinov and carbapenemov.

Drugs

  • Aztreonam
  • Azaktam