Doksilan

Roman name

Doxylan #

The composition and the form of

1 tablet contains doxycycline giclata 115.4 mg, or 100 mg doxycycline grounds; blistere in 5 or 10 pieces. or doxycycline monohydrate 208.2 mg, or 200 mg doxycycline grounds; blistere in 5 and 10 pc. , in the box one blister.

Of drugs

Sun. Blocking protein synthesis in cells sensitive microorganisms.

Farmakodinamika

Active against grampolaugitionah microorganisms : aerobic kokkov, Staphylococcus spp. (incl. producyruth penitsillinazou), Streptococcus spp. (incl. S. pneumoniae), aerobic sporoobrazuth (Bacillus anthracis), nesporoobrazuth bacteria (Listeria monocytogenes), and anaerobic sporoobrazuth (Clostridium spp.) bacteria; to a number of micro-organisms gramotricationah : aerobic kokkov, Neisseria gonorrhoeae, Neisseria meningitidis, aerobic bacteria, Escherichia coli, Shigella spp. , Salmonella spp. , Enterobacter spp. , Klebsiella spp. , Brucella spp. , Haemophilus influenzae, Bordetella pertussis. Moreover, the growth stops Klebsiella spp. , Treponema spp. , Mycoplasma spp. and Chlamydia spp. To more sustainable doksitziklino Pseudomonas aeruginosa, Proteus spp. , Serratia spp. Most strains of Bacteroides fragilis.

Indications

Infections of the respiratory system (pneumonia, bronchitis, empiema pleura), Lor-organov (pharyngitis, tonzillit, sinusit, otitis), stomach (including biliary tract); Urogenital infection (pyelonephritis, prostate, Dysmenorrhea, gonorrhoea, syphilis, chlamydia); Fatigue infections of the skin and soft tissues, osteomielit, curricular fever, brucellosis.

Pregnancy and lactation

Contraindicated in the second half of pregnancy.

Contraindications

Гиперчувствительност ь (incl. other tetratziklinam), a children's age (up to 8 years).

Side-Effects

Anorexia, flatulence, nausea, vomiting, disfagia, glossit, diarrhea, enterocolitis, pericardit, deterioration of the current red Lupus, haemolytic anaemia, thrombocytopenia, neutropenia, eozinofilia, tranzithornoe increase in liver blood transaminaz, alkaline phosphatase, cium, residual nitrogen candidiasis (percentage diarrhoea, glossitom, stomatitis, proktitom, vulvowaginitom) photosensitization, exfoliativei dermatitis, skin rashes, urticaria, anaphylacticskie reaction angioneuroticeski swelling.

Dosing and Administration

Inside. Adults and children weighing more than 50 kg-on the first day of 200 mg 1-2 admission; Then 100-200 mg per day. Children over 8 years with a mass of less than 50 kg-on the first day of daily intake at 4 mg / kg in one leap; Then 2 mg / kg / Sut.infection caused by the beta-haemolytic streptococcal Group A : treat at least 10 Dnei.gonorea : men on the 300 mg / day over a period of two to four days, or one day for every two 300 mg at intervals of 1 hour; women at the 200 mg / day for 5 Dnei.sifilis primary and secondary : 300 mg / day for a period of not less than 10 days.

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