Azelaic acid

Chemical name

Гептан-1,7-дикарбонова�� acid

Gross

C9-H16-O4

Of drugs

Drugs, the anti, anti, keratoliticescoe. And bakteriostaticescoy activity against Propionibacterium acnes and Staphylococcus epidermidis. Decreases fraction of free fatty acids in surface skin lipids. Proliferatiou stops keratinozitov and growth of abnormal melanocarcinoma. Clinical improvement occurred in an average of 2-4 weeks Lechenia.posle causing skin creams azelainova acid penetrates the epidermis and dermu, 3.6% absorbed by the system in the bloodstream. Excreted in the urine mainly unaltered, and some in the form of shorter dicarbonovykh acid formed as a result of oxidation.

Indications

Acne vulgaris, pathological hyperpigmentation (melazma).

Contraindications

Hypersensitivity, incl. to components of the drug (propilenglikolu).

Side-Effects

In rare cases (in the first 1-2 weeks of therapy) may irritate skin, stinging sensation.

Precautions

There is a need to avoid falling cream in the eye, the mucous membranes nose, lips and mouth. In cases of highly expressed skin irritation during the first weeks of treatment can be applied once a day or run that Preparat.sleduet award with caution during pregnancy and breastfeeding.

Dosing and Administration

Locally. The dosage and duration of therapy set individually. Shoe evenly and thoroughly scrub twice a day in the pre-treated (soft cleaning means and water) affected areas of skin. Time course for a few months (in the treatment melazma not less than three months). Again course possible after 1-2-mesyachnogo break.

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