Menthol

Chemical name

2-Изопропил-5-метилцик��огексанол-1

Gross

C10-H20-O

Characteristics

Clear crystals with a strong peppermint smell of pepper and cooling taste. Very little is soluble in water, it was easy to alcohol, ether, acetic acid, the fatty oils.

Of drugs

The drugs-mestnorazdrajatee, pain, distracting, protivozudnoe, antiseptic, soothing коронародилатирующее . The effect was primarily attributable reflectoriani reactions associated with irritation of sensitive nerve endings : pain receptors skin or mucous membranes promotes education and the release of endogenous bioactive substances (enkefalinov, endorfinov, peptides, kininov) for the regulation of pain, permeability receptacles and other processes providing pain, and diverting protivozudnoe effect. Antiseptic activity is indiscriminate defeat microbial cells. After biotransformiroetsa intake in the liver and out with the urine and jelchew of glukuronidov. Irritation (red) effect to reduce pain. Local accompanied by the loss of pressure, feeling cold rolling in the sense of light and stinging pokalawania. Kozhno-viszerle reflexes (Reflex arc does not affect the brain) improve trofiku tissues (respectively innervation zones). Whiskers changes tone receptacles both surface and deep in the tissues and internal organs. Dressing receptors mucous membranes of the oral cavity, raises spazmirovannah coronary. In small doses (oral use) has vetrogonnoe effect. Rezorbtivee effects in the employment of high doses are depressed AD and oppression CNS.

Indications

Inflammatory diseases of the upper respiratory tract (nose, pharyngitis, laringit, tracheitis), nevralgia, mialgia, artralgia, migraine, cardioneuroz, stenocardia (milder), itching dermatos.

Contraindications

Гиперчувствительност ь. It should not be used in children for lubricating chair.

Side-Effects

Allergic reactions (including contact dermatitis), ataxy, drowsiness, coma. The intranasal application in infants, patients, collapse; Smazawanyi in bed with children, eucalyptus oppression and stops breathing. The ingestion-pain in the abdomen, nausea, vomiting, dizziness.

Dosing and Administration

External, inhalation, route, inside. In neuralgia and mialgii that tumbled 2% alcohol solution or 10% oil mist; In zudath dermatozah 0.5% alcohol solution, or 1% ланолиново-вазелинов��й ointments, and migraines-oxidative skin temples mentolovam pencil, and inflammatory diseases of the upper respiratory tract, inhalation and drops in the nose, with light strokes forms under the language of 2-3 drops of alcohol solution to a piece of sugar or bread.

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