Bifonazole

Chemical name

1-([1,1'-Бифенил]-4-илфени��метил)-1Н-имидазол

Gross

C22-H18-N2

Of drugs

The drugs-antimycotic. Violate synthesis ergosterola cell membrane mushrooms and reduces its barrier function. There is absorbed in the local software absorbed 0.6% healthy and 2-4% inflammatory skin. T_1/2 skin is 19-32 hrs (depends on the density at the section of). Easily passes through shell fungus through 10-30 minutes zitozole a therapeutic (ingibiruty) level, the concentration in plasma is less than 5 ng / J

Indications

Dermatomikozy superficial kandidozy, dermatofitia, multicolored zoster, eritrazma, etc.; Onihomikozy.

Restrictions on the use of

Breast age.

Contraindications

Гиперчувствительност ь.

Side-Effects

Light skin or skin irritation, burning, pricking, contact dermatitis, the nail bed (treatment onihomikoza) - irritation, erythema, mazeration, peeling; Allergic reactions.

Specific guidance

In cases of allergic reaction to the plaster should use more watertight or wearing surgical napalchnikami.

Dosing and Administration

Nakozhno at night. Shoe and solution are thin in infected areas, and skin texture. Under dose per surface area of the size of the palm of the cream-column length of 5 mm, for the solution to 3 drops. Multiplicity of 1 per day. Duration of treatment is 2-4 weeks. The fungal diseases nails thin layer of cream to be hit fingernail, which turned Band and bandage for 24 hours After removal patch to replace his bandages need to be kept in warm water for about 1 minute; Razmagchennaya labor of nail removed shaberom. At the end of the sun off again without cream and turn Band. Duration of treatment to remove nail-7-14 days. After removing nail treatment continued for 4 weeks. Possible second course.

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