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Diflazon

See also Fluconazole

Roman name

Diflazon

The composition and the form of

1 capsule contains flukonazola 50, 100, 150 and 200 mg; in a contour acheikova package 7 pc. (50 and 100 mg) in box 1 and 4 are respectively 1 pc. (150 mg), in one box packaging and 7 or 10 pcs. (200 mg), in box 1 and 2 packages respectively.

Pharmacokinetics

Bioavailability after oral receive up to 90%, tying with blood plasma proteins, 11-12%, are distributed in the body, pervades all liquids, including spinnomozgovu liquid. C_max achieved through 0.5-1.5 h Do not metabolised, displayed in the main memory.

Indications

Tumours system, mucous membranes, vaginal; Kriptokokkoz (including chriptokokkovi meningitis and fungal infections of the lungs, skin, including in patients with immune deficiency), dermatomycosis (epidermofitia feet dermatomycosis, multicolored zoster, dermatofitia etc.).

Pregnancy and lactation

When pregnancy is possible if the expected effect of therapy outweighs the potential risk to the fetus. At the time of treatment should stop breastfeeding.

Contraindications

Гиперчувствительност ь.

Patient interaction

Increases concentration terfenadina, cizaprida, astemizola, fenitoina, cyclosporine, theofillina, indinavira, midazolama plasma blood slows down oral gipoglikemicakih funds derived sulfonylureas. Hydrochlorothiazide increases in plasma, rifampicin, increases metabolism.

Precautions

In patients with impaired liver should regularly monitor the activity of liver Fermentov.opat use in children under 6 years of age is limited.

Storage conditions

The temperature does not exceed 25 ° C

Shelf life

5 years

The registration

013210/02

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