Levorin

Chemical name

Antibiotics polienova structure.

Characteristics

Dark powder without smell and taste. Gigroskopichen. Easily destroyed by the action of acids and alkalis, as well as the light. Virtually nerastvorim in water and alcohol.

Of drugs

The drugs-antimycotic (fungicidal). A large number of violent double bonds with a high troponostew to sterinovm entities zitoplazmaticescoy membranes mushrooms. Communicating with them, induces uncontrollable membrane permeability makes (on the concentration gradient) exchange zitozolya components and the external environment and leads to lizisu cells. Once inside the little rats, and therefore does not have a system Actia.akteven against drojjepodobnykh fungi, in particular Candida kind, and some of the simplest (forming, leishmania, trichomona).

Indications

Tumours mucous membranes mouth, genitals, stomach, skin.

Contraindications

Hypersensitivity, the liver, pancreatitis, a disease hospital of stomach and duodenal ulcers, pregnancy.

Side-Effects

Diarrhoeal phenomenon : nausea, vomiting, diarrhoea, pain in the abdomen; Allergic reactions (skin itch and hyperemia skin).

Precautions

Pronounced side effects require the treatment. The monitor liver. Since no information on the use of levorin from breast-feeding women and children up to 3 years old, had to be careful in the appointment of these categories of patients.

Dosing and Administration

Inside. Adults 500,000 U 2-4 times / sutki. The course is 10-12 days. To rinse mouth (in the form of aqueous slurry 1:500), 2-3 times a day over a period of 15-20 Sutok.detam from 3 to 10 years for 125,000 U 3-4 times per day, from 10 to 15 years in the amount of 250,000 U 2-4 times / Sutki.mestno (ointment), cuticles affected sites 1-2 times a day for 7-10 Dnei.waginalno on 250000-500000 U twice a day for 14 days.

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