Pyrithione zinc

Chemical name

1-oksi-2 (1H) -piridintion zinc (2:1)

Gross

C10-H8-N2-O2-S2-Zn

Of drugs

The drugs-antimycotic, protivopsoriaticescoe, antimicrpobial. The range of actions includes several grampolaugitionah and gramotricationah bacteria, streptococci, staphylococci, and sinegnanuu intussusception wand protei, mushrooms, etc.; Provides bakteriostaticeski and fungistaticeski effect. Most active with respect to the bacteria Pityrosporum (Pityrosporum ovale, Pityrosporum orbiculare), one of the main factors of pathogenesis of inflammation, giperproliferation ability to psoriasis, seborrhea and other skin diseases. The electoral zitostaz, incl. skin cells under giperproliferation. 4-3 cell membranes that regulate the activity of some enzymes membranosvazannah. Contains поверхностно-активны�� component (metil-etil-sulfat), increases the permeability of skin to the active substances and providing for rapid resorption and infiltration of the deep layers of epidermis. Has expressed gidratiruta активностью.Накаплив��ется in the deep layers of epidermis, to a small extent enters the blood system.

Indications

Psoriasis, eczema, itching, dermatitis, neirodermit, palliative, inflammation and increased peeling skin; Disease caused by the bacterium Pityrosporum (a multicolored zoster, seborainey dermatitis), eritrazma. To shampoo : psoriasis of the nails head palliative, dandruff, itching of the skin.

Contraindications

Гиперчувствительност ь.

Side-Effects

Local allergic reaction, dryness and irritation of the skin (caused by prolonged or excessive use shampoo).

Precautions

Is not recommended in conjunction with the local drug action containing glukokortikoida. If your any of the forms in the eye must be washed them plenty of cold clean water, if swallowed, flush stomach, a severe drinking salt laxatives.

Dosing and Administration

External. Aerosol raspalaut the affected areas from a distance of 15 cm 2-3 times a day to a clinical effect and in the week after the disappearance Simptomov.krem are thin in the affected areas 2-3 times a day for five weeks to treat, two weeks, with the oily (in the re-escalation) in other diseases, to the complete disappearance of symptoms; shampoo : wash the head two or three times a week for two weeks, in the future, if necessary.

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