Directory Antineoplastic funds Antineoplastic hormonal and hormone antagonists Bilem
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Bilem

See also Tamoxifen

Roman name

Bilem

The composition and the form of

1 tablet contains tamoksifena citrate 10, or 20 mg; blistere in 10 pcs. , in a cardboard box 10 blisters.

Of drugs

Antiestrogennoe, protivoopujolevoe. Does the estradiolom for linking a estrogennami zitoplazmaticakimi receptors in organah-misheniah and hinders estrogenretseptonego complex with endogenous ligand-17-beta-estradiolom.

Indications

Breast cancer (in postmenopauzne period), cancer of the uterus (launched uniforms) anovulatornoe infertility.

Contraindications

Pregnancy, lactation (nursing women should give up breast-feeding).

Side-Effects

Loss of appetite, nausea, vomiting and other gastrointestinal disorders, hyperemia with a sense of warmth, vaginal bleeding or allocation, disorders of menstruation, brain, gipercalziemia and peripheral oedema, skin genitals, depression, headaches, dizziness, pain treatment, eye, corneal thickness and retinitis temporary anaemia, skin rashes.

Overdosing

Treatment of symptomatic.

Dosing and Administration

Inside. In endometrium cancer : 20-30 mg 1-2 times a day, the breast cancer : 20-40 mg 1-2 times a day, the barrenness anovulatornom : 10 mg twice a day for four consecutive days, beginning with the 2nd day of menstruation. Subsequent 4-dnevnykh cycles can be increased dose to 40 mg twice a day.

Storage conditions

table. : List B. In the dark spot

Shelf life

table. : 2 grams.

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