Klimara

Roman name

Climara

The composition and the form of

1 Plastury-tts area 12.5 cm ^ 2 seconds of 3.9 mg; in the laminated bag 1 pc. , in box 4 meshocka.

Pharmacokinetics

Estradiol released from the patch (daily 50 µ g) and trancdermalno enters the bloodstream at a constant speed, maintaining a level of hormone plasma.

Indications

Substitution hormonal therapy with problems caused by natural or surgical menopause (only in the case of diseases) : vazomotorne symptoms (hot flashes, sweating), sleep disturbance, atroficskie процессы.Предотвраще��ие postmenopauznogo osteoporosis.

Pregnancy and lactation

Contraindicated in pregnancy. At the time of treatment should stop breastfeeding.

Contraindications

Hypersensitivity, tumors of breast, endometriosis, liver tumors, tumors that depend on sex steroid hormones, vaginal bleeding unclear etiology, embolic processes (throm, X), pregnancy, breast-feeding.

Precautions

Before applying to the full general medical and gynaecological examinations (including the study of breast, cervical cytology testing), the exclusion of pregnancy. It should not be placed tarpaulin to the area of the breast or waist. If wounds suffered correctly, it is possible to take a bath or shower, but it should be borne in mind that the hot water may tarpaulin otkleitsa. There is a need to inform the treating physician of the existence of diabetes mellitus, hypertension, the varicose veins, otosclerosis, MS, epilepsy, porfirii, tetanii, low horei, heart failure, disorders of the liver or kidney, migraines, as well as the simultaneous admission of barbiturates, fenilbutazon, gidantoina, rifampitina, the emergence of irregular bleeding or unusually heavy bleeding in the period between the application of the drug, negative feelings in epigastralna Oblasti.v treatment, it should be noted that long-term use of estrogen to menopausal could lead to the hyperplasia of endometrium and increase the risk of developing cancer endometrium. To reduce the risk of cancer of endometrium require additional admission progestagen (typically within 10 to 12 days a month), which leads to the transition mucous membrane in the uterus secretornuu phase with its investigations and subsequent менструальноподобном у bleeding after cessation of progestagen.

Dosing and Administration

Nakozhno by removing the protective film, adhesive surface appliciruut (holding tightly to the surface of the skin for 10 seconds) for the net, healthy, defatted station skin bottom of the body once a week. Therapy are permanently or intermittently for one hour after each 3-nedelnogo period of the preparation. Hanna changed once a week. The event otkleivanii patch is replaced with a new one. The patients without uterus should use Aciclovir estrogenami in all other cases being progestagen appropriate doses for 10-12 days each month. When selecting a lengthy treatment progestagenom, it can be initiated at any time and must be repeated regularly at intervals of about four weeks.

Storage conditions

List B. The temperature is not above 30 ° C

Shelf life

3 years

The registration

015577/01

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