Megas

Roman name

Megace #

The composition and the form of

1 tablet contains megestrola acetate 40 or 160 mg; in vials of 100 pcs. , in the box one bottle.

Of drugs

Protivoopujolevoe, gestagennoe. Suppress products seconds and androstendiona adrenal has zitotoksicescoe impact on the гормоночувствительны е cell tumors and suppresses liberatiou a factor in their growth. Does education and kahectina interleikina-1 or effect.

Pharmacokinetics

After intake of rapidly absorbed from the digestive tract. C_max achieved in 2-3 hours T_1/2 - 2-3 days. Return with urine (57-78%) and faeces (8-30%).

Indications

Disseminated breast cancer, cancer of endometrium, anorexia and cachexia in cancer patients and people with AIDS.

Contraindications

The first four months of pregnancy.

Side-Effects

Krovanistye separated from the vagina; Rarely Delay fluid throm, Itsenko syndrome - Kushinga (iatrogenic).

Precautions

It should not be used in the diagnosis of pregnancy. Caution to appoint tromboflebite, even in history. Megas not preclude surgical, chemotherapeutic or radiation treatment of cancer.

Dosing and Administration

Inside, or one of a few (2-4) receptions. In disseminirovannom breast cancer by 160 mg per day; With anorexia and cachexia in cancer patients and AIDS patients, 480 mg (or more) per day.

Storage conditions

table. : List B. The temperature of 15-25 ° C. Избегать хранения при температуре выше 40°C.Avoid storage at temperatures abov