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Dilatrend

See also Carvedilol

Roman name

Dilatrend

The composition and the form of

1 tablet contains carvedilola 6.25, 12.5 or 25 mg; blistere in 10 pcs. , in a cardboard box three blisters.

Indications

Long cardiac failure, hypertension essencialnaya, stenocardia.

Contraindications

Hypersensitivity, asthma heart failure (class IV), chronic obstructive lung diseases, asthma, aetiology (heavyweight), the weakness syndrome sinusnogo unit shock liver failure, pregnancy, lactation (for the period of treatment should abandon breastfeeding)

Side-Effects

Headache, dizziness, weakness (often at the beginning of treatment), aetiology, ortostatical hypotension, nausea, pain in the abdomen, diarrhoea, allergic skin reaction (exantema, urticaria, itching, skin), pain in the extremities; rarely AV blockade worsening symptoms peremejateisa hromota, progression of heart failure, reducing slezootdelenia.

Patient interaction

Potenziruet of insulin, oral and saharoponijath antigipertenziveh funds. Diltiazem, digoxin, digitoksin can contribute conductivity (increase the time of the AV). Inductive oksidaz mixed functions (rifampicin) weaken effect; Inhibitors oksidaz mixed functions (zimetidin) increase. Anaesthetics reinforce negative effect inotroponoe carvedilola.

Overdosing

Currently, the cases of drug overdose Dilatrend were reported.

Precautions

In heart failure (in the background reception dioretikov and ACE inhibitors) to reduce excessive AD which eliminates the lower dose dioretika or ACE inhibitor. Be wary appoint people who will be working with machines and mechanisms (including administering vehicles), - reduced rate of the reaction (especially while admission alcohol). When combined with a antiaritmikami (including calcium antagonists) past should not be accepted as / 386/1989 Safety and effectiveness in the age of 18 years have not been established.

Dosing and Administration

Inside, squeezed enough liquid. In essencialna hypertension, 12.5 mg once a day for the first 2 days then to 25 mg once a day, with the possibility of a gradual increase in dose at intervals of not less than 2 strokes Ned.pri 12.5 mg once a day first 2 days then to 25 mg twice a day (up to 100 mg in 2 admission). In congestive heart failure on 3.125 mg twice a day for two weeks, then (with good endurance) to 6.25 mg twice a day, further to 12.5 mg to 25 mg twice a day (at body mass index less than 85 kg maximum dose is 25 mg twice a day, the mass of more than 85 kg to 50 mg twice a day). If the treatment was suspended for more than two weeks, then resume it in the dose of 3.125 mg twice a day, with a subsequent increase doses.

Storage conditions

List B. In the dark place at a temperature of no higher than 25 ° C. Storage on the world may change color tablets.

The registration

009,420 (Ann.2001)

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