Dihalroergotoxine

Characteristics

Digidrirovannoe derivative of alkaloids LPV (ergochristina, ergocornina, ergokriptina)

Of drugs

The drugs-sossoudorasshiratee (arteriodilatirtee) gipotenzivne. Does pre - and alpha postsinapticalkie adreno- and dofaminergicakie receptors prevents linking norarenalina and start postsinapticakimi discs, pressornoe suppresses the rest. Passes gistogematicalkie barriers, including GEB, placental. It dilatatia peripheral vessels, reduces variation increases the synthesis and release norarenalina increases airway diseases. Impact intensity anaerobic metabolism and stimulates oxygen tissues brain, activates metabolism vnutricletocny functionally damaged neuronal operates on neurochemical processes in aging brain tissue.

Indications

Psihoorganiceski syndrome in old age, disease peripheral arteries (functional human peripheral blood circulation, a disease syndrome and Reynaud, neirogenne arterial spasm, Sudek syndrome), a disease Burger, obliteriruty ulcers, diabetic angiopatia, causes arteries in trombozah, tromboflebitah, varikozny syndrome, a breach of cerebral circulation (migraine, vazomotorne headaches, ulcers of the brain events acute or chronic cerebrovascular insufficiency), vertebrobaziliarnaya failure, ischemic stroke condition after haemorrhagic stroke or traumatic brain damage, arterial hypertension, of retinal blood vessels and skin eyes, retrobulbarnyi rapid, Ménière syndrome, kohleovestibularnyi syndrome vascular origin.

Restrictions on the use of

Aetiology Arterial gipotenzia.

Contraindications

Hypersensitivity, heavy forms of ischemic heart disease, the kidneys function, aged age.

Side-Effects

Anorexia, diarrhoea events (nausea, vomiting, the severity of epigastrii), pains in the abdomen, impaired vision, zalojennosti nose, ortostatical hypotension, skin rashes.

Specific guidance

Quick in / in the introduction could cause ortostaticescuu hypotension.

Patient interaction

Do effect sosudorasshirath and antigipertenziveh funds proximity anti weakens - alfa-adrainomimetikov, incl. clonidine.

Dosing and Administration

Inside, and food for 1-1.5 mg (40 drops or 1 table.) 3 times a day where appropriate dose to 4.5 mg can be taken once a day. In severe cases may simultaneous oral and injecting, and the dose to the liver (p / c in / m in / in drip) up to 0.3-0.6 mg. For acute human cerebral circulation, postinsultnykh and traumatic injuries brain appoint ability mg / day in / drip in for the first 10 to 15 days, Further treatment continues lower doses. The duration of the case.

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