Darob

Roman name

Darob #

The composition and the form of

1 tablet contains sotalol hydrochloride 80 and 160 mg; blistere in 10 pcs. , in the box two blister.1 USD 4 ml solution for injection 40 mg.

Of drugs

Antiaritmicescoe. Beta-adrainoretseptora block.

Indications

Supraventrikuliarnae tahiaritmii (tachycardia from AV connections supraventrikuliarnaya tachycardia in Wpw-sindromom, Paroxysm predserdy times), ventricular tachycardia.

Pregnancy and lactation

Only for health reasons (for 48-72 hours before expected delivery to the reception).

Contraindications

Гиперчувствительност ь (incl. to sulfonamidam), female heart failure III extent shock, AV blockade II and III extent sinoatrialnaya blockade syndrome weakness sinusovogo unit aetiology, gipokaliemia, gipotenzia elongated QT interval, occluzirute defeat peripheral arteries, obstructive lung diseases, metabolic acidosis, laryngeal edema, allergic rhinitis.

Side-Effects

Headache, dizziness, drowsiness, fatigue, cooling off; Rarely is a violation of the stomach, bronhospazm, skin reactions, sleeping, increased symptoms of heart failure, aetiology, violations of AV conduction, gipotenzia; slezootdelenia decline, hypoglycaemia, hallucinations, dry mouth, muscular convulsions, passing impotence, the vision, conjunctivitis.

Patient interaction

Coupled with nifedipinom, tricyclic antidepressants, barbituratami, derivative fenotiazina, drugs, vazodilatatorami, dioretikami and other hypotensive drugs is a significant decrease in norarenalinom and MAO inhibitors, a sharp increase in AD. Drugs and противовоспалительны е to reinforce cardiodepressivny effect. Could enhance neuromuscular blockade against tubokurarina. Reserpine, clonidine, alfa-metildofa, guanfation, heart glycosides increase pronounced negative chrono and dromotroponogo action. Increases the effect of insulin and oral gipoglikemicakih (especially in the face of physical activity).

Overdosing

Symptoms : fatigue, increased inhibition, loss of consciousness, mioclauniceskie Generalized convulsions, gipotenzia, aetiology (with asistoliei) jeludockove tachycardia (atypical) cardiogennogo symptoms and hypovolemic Shoka.lechenie : removing the drug from the body (stomach wash, Hepatology); introduction of atropine, dopamine, izoprenalina, sports, glukagona shown.

Precautions

Not recommended simultaneous reception antiaritmicakimi hinidinpodobnami drugs. Be wary appoint diabetes, feohromotsytome, violations of the kidneys and liver, cardiac infarct (in history), psoriasis, those in the diet. Avoid abrupt cessation of treatment (perhaps the syndrome "lifting").

Dosing and Administration

Inside, the food, with a small amount of water on the 160 mg (1 tab. 160 mg or 2 table. 80 mg) twice per day or 80 mg (1 tab. 80 mg) three times a day; patients with creatinine Cl within 10-30 ml / min dose reduced by half; in the Cl creatinine less than 10 ml / min using 1 / 4 the recommended doses. In / in introducing occasional dose of 20 mg, the reintroduction of a possible 20 minutes.

Storage conditions

r-r d / in. : List B. In temperaturetabl room. : List B. The temperature is not above 25 ° C

Shelf life

r-r d / in. : 2 g.tabl. : 5 years

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