Directory → Wegetotropona funds → Adrenomimeticalkie funds → Alfa-adrainomimetiki → Gutron
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GutronSee also MidodrineRoman nameGutronThe composition and the form ofPill-1 tabl.midodrina hydrochloride 2.5 mgu- 5 megawatts blistere 10 pcs. ; In a cardboard box two Blister.kapli for admission into the 1% - 1 mlmidodrina hydrochloride 10 mg (approximately 120 mg of ethyl alcohol), 1 ml = 30 ml kapelvo dark glass on the 10, 20 or 25 ml; In a box one bottle.PharmacokineticsThe oral application is rapidly absorbed, becoming active metabolite. Following in / injections in the developing relatively slowly and continues for a long time. T_1/2 metabolita active plasma is 3-4 hours Due to the very low liquid barely penetrates through GEB. Midodrin and its metabolites are with urine almost completely within 24 hoursFarmakodinamikaIncreases tone force on resistance arterial pressure increases AD and hampers (with orthostatic violations), the stagnation of blood in venoznom course. This results in the continued constant volume of circulating blood and AD increased delivery of blood to the organs and remove orthostatic violations. No direct effect on the heart, the central nervous system (no sleep disturbance). Improves the pouches bladder.IndicationsGipotenzia (by the admission of psychotropic drugs symptomatic during convalescence after surgical interventions, childbirth, etc.), ortostatical gipotenzia (with the regulation violations and blood circulatory desregulyatsiah with reactions by type and simpatikotonia asimpatikotonia, idiopathic, secondary); Gipotonicescie reaction (changes in the weather, the morning with a propensity for low AD); self urinating (with the problems of tumours bladder).Pregnancy and lactationAcceptable, but only after consulting a specialist.ContraindicationsHyperten, zakratougolnaya glaucoma, feohromotsytoma, Ray, acute cases, severe kidney failure, mechanical obstruction of urinary tract infections, prostate adenoma cancer to the presence of residual urine.Side-EffectsViolation of a heart rhythm, a pain in the heart, allergic reaction (rash).PrecautionsThe heavy losses of organic cardiovascular system, human heart rhythm and kidney function requires a mandatory correction mode. Particular attention to the dosing draw in the case of treatment hypotonia caused by weather changes, to identify hypertension in history. With long-term use, or after intensive course it is necessary to investigate the kidney.Storage conditionsList B. In the dark place at a temperature of no higher than 25 ° CShelf life2The registration015880/01 |
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