Beta-adrainomimetiki

The group

This group includes adrenomimetiki inciting beta-adrainoretseptora only. They emit selective beta_1-, beta_2-adrainomimetiki (izoprenalin, jortziprenalin), and selective : beta_1-adrainomimetiki (dobutamin) and beta_2-adrainomimetiki (salbutamol, fenoterol, terbutalin et al). As a result of an бета-адренорецепторо�� Membrane activated adenilatziklaza and increases intracellular calcium. Beta-adrainomimetiki selective increase the strength and frequency of heart while rasslabla smooth muscle bronchi. The unwanted tachycardia limits their use in kupirovanii bronchoconstriction. Instead, selective beta_2-adrainomimetiki have found widespread application in the treatment of asthma and chronic obstructive lung diseases (chronic bronchitis, emphysema, etc.), as they have fewer side effects (on the heart). Beta_2-adrainomimetiki appoint and dropped, and the interior, but the most effective dose.
Selective beta_1-adrainomimetiki greatly increased effect on the heart muscle, causing a positive foreign, and the chrono batmotropony effect and the less a reduced CSO. They are used as aids in acute and chronic heart failure.