Oxis turbuhaler

Roman name

Oxis Turbuhaler

Pharmacokinetics

Bronhodilatiruty effect of a single dose is after 1-3 minutes and lasts 12 hours C_max recorded in 15 minutes, tying the plasma protein-50%, T_1/2-8 pm The liver and O-demetiliruetsa kongugiruetsa glukuronova with acid. In light up 28-49% ingaliruema doses. Neither is the vdahaemam air (21-37% weighted dose); Presented with urine unchanged to (6-10%).

Clinical pharmacology

Therapeutic effect was achieved after 1-3 minutes and lasts 12 hours after a single dose.

Indications

Obratimaya obstruction of the respiratory tract (prevention and long-term therapy in combination with противовоспалительны ми drugs, including inhalants steroidami).

Pregnancy and lactation

When pregnancy with caution only on strict conditions. There should be appointed for the period of breastfeeding.

Contraindications

Гиперчувствительност ь to formoterol or lactose.

Side-Effects

Frequently (more than 1%) : headache, tremor, Tahikardia.inogda : initiation, anxiety, insomnia, muscle Sudorogi.redko (less than 0.1%) : bronhospazm, gipokaliemia, skin rashes, urticaria.

Patient interaction

Effect weaken beta-adrenoblokatora (including in the form of eye drops). Derivative xantina dioretiki and increase the risk gipokaliemii.

Precautions

The caution should be applied to tireotoxicose, heavy heart disease (CHD, tahiaritmia expressed heart failure); Diabetes (requiring periodic monitoring of blood glucose).

Storage conditions

List B. At temperatures below 30 ° C. Turbuhaler after the store closed tightly seals

Shelf life

The registration

013937/01-2002

The drug forms

Plastic inhaler containing round granules from white to white with a blue-coloured broken in fine powder with little pressure. Perhaps the powder faction.

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