Aprofene

Chemical name

2-(Диэтиламино)этиловы й broadcast �льфа-метил-альфа-фени лбензолуксусной acid (and as hydrochloride)

Gross

C21-H27-N-O2

Characteristics

The white crystalline powder. It is soluble in water and ethanol. Termoustoytchiv Solutions.

Of drugs

Drugs, the skin, sossoudorasshiratee. Competitive blocking central and peripheral m and n holinoretseptora. Impact tone and airway smooth muscles syndrome (spasmolytic effect). Increases Oxytocics activity contributes to the disclosure cervix during delivery; More coronary vessels.

Indications

Spasticskie colita, liver, kidney cramps, holetsistit, pilorospazm, saying disease stomach and duodenal ulcers, arteriosclerosis cerebrovascular, endarteriit, poor tribal activities.

Contraindications

Glaucoma, Denmark prostate cancer, acute kidney and liver failure.

Side-Effects

Brown mouth, disfagia, thirst, nasal irritation of the stomach, constipation, oppression CNS, the coordination and increasing vnutriglaznogo pressure, urine retention.

Patient interaction

Sedative effect reduces caffeine.

Overdosing

Symptoms : dizziness, a feeling of intoxication, hallucinations, agitation, headache, paralysis ccomodation strengthening peripheral holinoliticakih effects; Already, disruption of breathing and sossoudodwigatelnogo Centra.lechenie : introduction antiholinesteraznah funds detoksicazionnaya therapy.

Precautions

Do not travel to appoint without the release of the patients whose occupation requires a rapid response.

Dosing and Administration

Inside, the food-to 25 mg up to 4 times a day, the long-term; Highest daily dose of 100 mg, single-30 mg. Parenteral (p / c in / m) - 1 ml of 1% solution, the highest single dose of 20 mg daily to 60 mg.

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