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BaralguetasSee also BelladonnaRoman nameBaralgetasThe composition and the form of1 tablet contains metamizola sodium 500 mg, pitofenon hydrochloride 5 mg and fenpiverinia bromide 100 g; blistere in 1910 st.1 peeling from 5 ml solution for injection-sodium metamizola 2.5 g pitofenon hydrochloride 10 mg and fenpiverinia bromide 100 g; in a Box 5 pcs.Of drugsAnalgezirutee, tissue, cough. Does ziklooksigenzu and reduces synthesis of GHGs. The relaxation of smooth muscles through direct miotroponogo and holinoliticski action.PharmacokineticsIf ingestion is part of the preparation metamizol sodium rapidly and completely absorbed. T_1/2 achieved through 1.4 hours Metabolised in the liver to education 4-n-metilaminofenazon, analysed, 4-N-ацетиламинофеназон а and 4 -N-формиламинофеназон��. T_1/2 the metabolita 4-n-metilaminofenazon is 1,8-4,6 hours Penetrates through the placenta and breast milk. Report from the body through the kidneys.IndicationsSpasticskie pain and cramping, especially in the area of stomach, biliary and urinary tract, the interior of the reproductive organs in women.Pregnancy and lactationContraindicated in the first trimester and in the last 6 weeks of pregnancy; To the rest periods pregnancy appointed only on strict conditions and under the supervision of a physician. Application for nursing mothers requires a breastfeeding.ContraindicationsГиперчувствительност ь (including to the individual components drug to pirazolona derivative), metabolic disorders (porphyria liver, congenital glukozo-6-fosfatdegidrogenaza deficit), the victim loses consciousness, tahiaritmia, zakratougolnaya glaucoma, Denmark prostate cancer with the trend to the accumulation of residual urine, mechanical stenoses blood, megakolon; for the injection solution, a young child (up to 3 months) or weight less than 5 kg; tablets for-age children (up to 5 years).Side-EffectsThe sharp fall AD oliguria, anuria, proteinurija, agranulozitos, lakopenia, thrombocytopenia, or anaphylacticskie anaphylactoidnye reaction, urticaria, lesion close-mucous membrane chair, the syndrome of Stevens-Johnson, Laiella syndrome, pain at the injection.Specific guidanceSolution inconsistent (in one sprite) with any other drugs. Injections should be appointed only when ingesting impossible (or broken skin of the stomach). At the time of treatment urine can be red (is one of the metabolites, and the blood sugar glukozoksidaznam method may give a lower results).Patient interactionDo antiholinergicakie effects hininsoderjath drugs. Impact cyclosporin concentration in the plasma. When coupled with the use of alcohol is increasing mutual effects.OverdosingSymptoms : dry mouth, decreased sweating, violation ccomodation, difficulty urinating.PrecautionsA special caution in a 2 ml, and the solution (risk of a sharp fall AD). In / in the injection should be slowly (at a rate 1 ml / min), in the trunk and under the supervision of AD curves and frequency of breathing. Only strict testimony appoint patients with sistolicescoe pressure below 100 mm Hg or hemodinamics unstable. In bronchial asthma, chronic инфекционно-воспалит��льных respiratory diseases, the symptoms such as hay fever, chronic krapiwnice; suffer from frequent or kongunguitami rinosinusitami having history reaction �иперчувствительност�� nelekarstvenne the substance or NPVS analgetiki-antipiretiki; in the ear or expressed bolevom syndrome possible attacks suffocation and shock of the (probability of shock significantly higher after in / introductions). In identifying гиперчувствительност и should warn patients against receiving further drugs containing pirazolon. Suspects of agranulozitos or if trombozitopenia must stop receiving medication.Dosing and AdministrationAdults and adolescents over 15 years of age, one-time dose-1 table. or 2 ml in / in or / m; maximum daily intake - 8 table. (2 table. 4 times a day), or 10 ml (5 ml twice a day). Children between 12 and 14 years of age (weighing about 50 kg), one-time dose-1 table. or 0.8 ml; maximum daily intake - 6 table. (on the table 1.5. 4 times a day), or 6.4 ml (for the 1.6 ml of 4 times a day). Children 8-11 years (weighing about 33 kg), one-time dose Table 0.5. or 0.5 ml; maximum daily intake - 4 table. (1 tab. 4 times a day) or 4 ml (1 ml 4 times a day). Children 5-7 years (weighing about 24 kg), one-time dose of 0.5 table. or 0.4 ml; maximum daily intake - 2 table. (on the table 0.5. 4 times a day), or 3.2 ml (for the 0.8 ml of 4 times a day). For children 3 to 4 years (weighing about 18 kg), one-time dose of 0.2 ml; maximum daily dose of 2.4 ml (for the 0.6 ml of 4 times a day). Children between 1 and 2 years (weighing 12-14 kg), one-time dose of 0.2 ml; maximum daily dose of 1.6 ml (for the 0.4 ml of 4 times a day). Children 6-11 months (with a body weight of 10 kg) product introduced only in the / m, single dose 0.1 ml; maximum daily dose of 1.2 ml (0.3 ml 4 times a day). Children 3-5 months (weighing 5,5-7,5 kg), only / m, single dose 0.1 ml; maximum daily dose of 0.8 ml (for the 0.2 ml of 4 times a day). With the pills alone squeezed more liquid. Before the introduction of injection solution (in / in or / m) ampoules should keep in his hand.Storage conditionsr-r d / in. : In dry the dark place at a temperature of no higher than 25 ° Ctabl. : In dry the dark place at a temperature of no higher than 25 ° CShelf lifer-r d / in. : 5 lettabl. : 5 years |
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