Trigan-d injections

Roman name

Trigan-D injection

The composition and the form of

1 USD 2 ml solution for injection contains ditzikloverina (ditziklomina) hydrochloride 20 mg; in a Box 5 st.1 tablet coated liner contains ditzikloverina (ditziklomina) hydrochloride 20 mg dose and 500 mg; in a carton strip 10 to 10 pcs.

Of drugs

Skin, analgezirutee.

Pharmacokinetics

Ditziklomina hydrochloride from oral appointment faster absorbed when administered and accumulate the necessary concentration in the blood plasma through 60-90 minutes. T_1/2 1.8 hours Excreted in the kidneys (79.5%). Paracetamol quickly and completely absorbed with the ingestion. C_max through 1hr Analgezirutee effect occurs within 30 minutes and a maximum in 2 hours

Farmakodinamika

And antiholinergicescoy activity and directly relaxes smooth muscles (ditzikloverin); Removes pain (paracetamol).

Indications

Colica (intestinal, liver, kidney), dismenorea.

Pregnancy and lactation

Nursing mothers should stop breast-feeding.

Contraindications

Hypersensitivity, obstructive disease syndrome, and pechenerngo urethra path, heavy ulcerative cramps, reflux-ezofagit, the precarious state of the cardiovascular system in acute artistic methods, glaucoma, male gravis, a children's age (up to 6 months).

Side-Effects

Dizziness, drowsiness, decreased sweating, dry mouth, nausea, constipation, loss of taste and anorexia, a disorder increase vnutriglaznogo pressure, allergic reactions.

Patient interaction

Effect increase amantadine, antipsihoticalkie agents, benzodiazepines, MAO inhibitors, narcotic analgesics, nitrate and nitrite simpatomimetiki, Tricyclic antidepressants, holinolitiki, corticosteroids, lower-antatsida. - Increases of digoxin.

Precautions

Be wary appoint, with a high temperature of the environment (as a result of reduced odor increased likelihood gipertermii and thermal shock). In patients receiving antiholinergicakie drugs, it might be psychosis, sputannosti consciousness, disorientation, short-term memory loss, hallucinations, dizartria, ataxy, coma, euphoria, weakness, insomnia, agitation inadequate emotional reaction (symptoms reduced by 12-24 h after declining dose).

Dosing and Administration

V / m. Adults : 2 ml once (when expressed pain-again, at intervals of 4-6 h). Inside, in the table 1-2. 3-4 times a Sutki.detam : 0-6 age 1/4-G table. , 7-12 years 1/2-1 table. 3-4 biennially day.

Storage conditions

r-r d / in. : List B. In dry the dark place at a temperature of no higher than 30 ° C

Shelf life

r-r d / in. : 2 grams.

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