Imechin

Chemical name

2,2,6,6-Тетраметилхинукл идина yodmetilat

Gross

C12-H24-I-N

Characteristics

The white crystalline powder bitter taste. Easily soluble in water and alcohol.

Of drugs

The drugs-ganglioblokirtee. Does n-holinoretseptora vegetative gangliev dampens of nervous stimulation to preganglionarnah postganglionarnae Evoked parasimpaticalkie and fiber. Due to the reduced revenue vazokonstrictornah sympathetic impulses to receptacles and the peripheral arterial bed was reduced AD. The gipotenzivnogo action is 4-20 min after cessation of AD recovering from 4-15 min. Gipotenzivny effect is short, dependence on dose and good handling. The peripheral vessels by depositing blood on the periphery and the reduction of bleeding in the area of operational fields (used for controlled hypotension in anesthesiological practice). Prevents development vegetative negative reactions from the internal organs and vessels operating in the interventions. Blocking the nerve impulses through the week ganglia, modifies functions of receiving innervaciu nerves, and it was a violation ccomodation eye midriaz, the bronchi, reducing motor activity of the digestive tract, oppression secreting glands, muscle loss bladder. Decreases impact of the heart, does not alter or more increases the blood brain (zerebrovskulyarnoe resistance decreases more than CSO). Poor drawn from the alleged ill-permeates through GEB.

Indications

Hypertonic kriz managed gipotenzia, black lungs and the brain.

Contraindications

Hypersensitivity Arterial gipotenzia, shock, myocardial infarction (acute stage), pulmonary, liver and / or kidney failure, degenerative changes in the central nervous system and it zakratougolnaya glaucoma.

Side-Effects

From the nervous system and sensory organs : weakness, dizziness; Midriaz violation ccomodation Glaza.so the circulatory system and blood (blood, gemostaz) : ortostatical gipotenzia, Tahikardia.so part of the intestine : dry mouth, atony Kishechnika.so the urogenital system : atony bladder.

Specific guidance

0.01% solution for the on / drip in a train by breeding 1 ml 1% solution of 100 ml izotoniceski (0.9%) solution of sodium chloride or 5% glucose solution. If the gipotenzivne Effect after the 0.01% solution can increase a solution to 0.02%.

Patient interaction

Gipotenzivny effect of the rise in the application ftorotanovogo narcosis and tubokurarina.

Overdosing

Symptoms : ortostaticeski Kollaps.lechenie : making sick of the pripodnatami legs introduction adrenomimetikov and analeptikov (nicetamin, caffeine).

Precautions

The preparation should be under the control of AD Systems. With the aim of preventing the development of ortostaticski collapse, it is recommended that the period of 2-2.5 h after injection patients retain the rest.

Dosing and Administration

In / in, drip, and run hypotension - 0.01% solution at the speed of 90 to 120 drops per minute at the speed of effect reduced to 30-50 drops per minute. B / struino in slow 0,005; 0,007; 0.01g (0.5; 0.7; 1 ml of 1% solution), 5; 7; 10 ml izotoniceski solution of sodium chloride or 5% glucose solution one or Batches 2-3 ml with a 3-4 minutnami intervals. Perhaps odnomomentnoe in / in a 10 ml 0.1% solution before proceeding to a drip.

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