Midokalm-richter

Roman name

Mydocalm-Richter

Characteristics

Miorelaxant central action.

Pharmacokinetics

Once inside well absorbed from the digestive tract. C_max blood is a 0.5-1 hour bioavailability is about 20%. Metabolised in the liver and kidneys. Pharmacological activity of metabolites is not known. Report the news in the form of metabolites (more than 99%).

Farmakodinamika

Impact pathologically increased muscle tone and rigidity of muscles, reduces pain, facilitates arbitrary active users. And weak inflammatory and adrenoblokirutm effects. Do peripheral blood regardless of the influence of central nervous system.

Indications

Treatment pathologically increased muscle strength and spasticity poperechno-polosta muscles as a result of organic disease of central nervous system (including the defeat of the pyramid, multiple sclerosis, stroke, mielopatia, encephalomyelitis); The treatment of high strength and muscle spasticity, muscle contractures accompanying diseases of the musculoskeletal system (including spondilez, spondiloartroz, zervikale and lumbale syndromes, arthritis major joints); - rehabilitation treatment after orthopaedic and emergency operations; , in a combination therapy obliteriruth diseases receptacles (obliteriruty ulcers, diabetic angiopatia, obliteriruty trombangiit illness Reynaud), diseases caused by disorders innervation receptacles (akrozianoz, intermittirutaya angioneurotical disbazia). Pill (optional) : Jimmy sklerodermia, in pediatrics is a disease Little (child brain paralysis), and other encephalopathies, causing muscular dystonia.

Pregnancy and lactation

During pregnancy (especially in the first trimester), and during the period of breast-feeding treatment Midocalmom possible only if the expected benefit to the mother outweighs the potential risk to the fetus.

Contraindications

Гиперчувствительност ь (incl. to lidokaino when Injecting a), infants, children up to 1 year (pills), a children's age (injecting).

Side-Effects

Muscular weakness, headache, reducing AD, nausea, vomiting, discomfort abdominalny (at the same time reducing the dose usually runs). In rare cases, allergic reactions (skin itch, erythema, urticaria, angioneuroticeski swelling, anaphylactic shock, breathing, bronhospazm).

Patient interaction

It may be used in combination with sedatives, hypnotics means and preparations containing alcohol. No impact on the alcohol on the central nervous system. Tolperizon aggravating niflumova acid (at the same time the application may require lower doses niflumova acid). Funds for general anesthesia and peripheral muscle, psychotropic drugs clonidine-reinforcing effect tolperizona.

Precautions

Apply strictly on doctor's prescription to avoid Oslojneni.midokalm no influence on the ability to drive and to the jobs and the increased risk.

Storage conditions

List B. In the dark place at a temperature of 15 ° C

Shelf life

3 years

The registration

014846/01-2003

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