Quateron

Chemical name

[3-[(п-Бутоксибензоил)о��си]-2-метилбутил]триэт иламмония iodide

Gross

C22-H38-I-N-O3

Characteristics

Monochetverticnoe ammoniewoye connection. White powder with a slightly yellowish sheen, bitter taste. Rat in the water and light heating.

Of drugs

The drugs-n-holinoliticescoe, ganglioblokirtee. Does n-holinoretseptora vegetative gangliev and hampers the transfer of nerve stimulation to preganglionarnah postganglionarnae week fibres. How to proceed in neurotransmission parasimpaticakih (more), and sympathetic gangliev. Braking impulses of the holinergicakim nerve fibers, leads to a reduction of motion activity decreases, oppression secreting glands. Provides koronarorasshiratee effect.

Indications

Ulcers disease stomach and duodenal ulcers, stenocardia, arterial hypertension.

Contraindications

Hypersensitivity, acute myocardial infarction, arterial gipotenzia, shock, the liver and / or kidneys, thrombosis, degenerative changes in the central nervous system and it zakratougolnaya glaucoma.

Side-Effects

Arterial gipotenzia, tachycardia, dizziness, constipation; Diarrhoeal phenomenon and gastralgia (in the early days of treatment in patients with gastric ulcers stomach and duodenal ulcers); Unpleasant feelings in the hearts and increasing attacks (in patients with stroke).

Patient interaction

Do adrenomimetikov effects (increased sensitivity adrenoretseptorov result of the erosion of sports and norarenalina). Gipotenzivny effect reduces Tricyclic antidepressants, reinforce Other gipotenzivee means (possibly combined application).

Precautions

When unpleasant feelings in the hearts and renewed attacks in patients with stroke drug should be lifted at 2-6 days, and to continue treatment at a reduced dose. If the side effects are, the treatment must stop.

Dosing and Administration

Inside, and ulcers : on 0.02 g 3-4 times a day for 3-4 weeks or more. When strokes (for the attacks) : initial dose of 0.01 g (at the reception), in 2-3 days off dose increased to 0.02 g; Frequency reception three times a day, with frequent attacks - 4 times a day. The course of treatment 3-4 weeks may re-apply after 10-12-dnevnogo break. In arterial hypertension : the 0.02 g 3-5 times a day; Treatment an average of three weeks. The maximum single dose for adults, 0.05 g daily dose of 0.2 g.

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