Temechin

Chemical name

2,2,6,6-Тетраметилхинукл идина gidrobromid

Gross

C11-H21-N.HBr

Characteristics

White or white with light kremovatam white crystalline powder. Very easily soluble in water, easily in alcohol.

Of drugs

The drugs-ганглиоблокирующее. Does n-holinoretseptora sympathetic and parasimpaticakih gangliev (delayed transfer of the case to preganglionarnah postganglionarnae fibre vegetative nerves), karotidnykh clubockov and hromaffinna napochechnikov tissue. Violate the nerve impulses through the week nodes and alters the bodies of innervaciu nerves. Decreases flow vazokonstrictornah impulses to receptacles, the adrenal glands, weakens pressorne reflex reaction expands peripheral vessels and lowers AD. It tachycardia, a violation ccomodation eye midriaz, the bronchi, reducing motion activity smooth muscles of the stomach, oppression secreting glands, muscle loss bladder. Does central n-holinoretseptora, oppressing CNS (sedative effect). Well drawn from the blood passes through the GEB.

Indications

Cramps peripheral vessels (including obliteriruty endarteriit and Reynaud syndrome); Sexually violent spasm smooth muscles of internal organs, including saying disease stomach and duodenal ulcers, arterial hypertension, including during pregnancy (pregnancy toxaemia).

Contraindications

Hypersensitivity Arterial gipotenzia, shock, myocardial infarction (acute stage), thrombosis expressed arteriosclerosis, liver and / or kidney failure, degenerative changes in the central nervous system and it zakratougolnaya glaucoma.

Side-Effects

From the nervous system and sensory organs : weakness, dizziness, the ccomodation eye Midriaz.so the circulatory system and blood (blood, gemostaz) : ortostatical gipotenzia, Tahikardia.so part of the intestine : dry mouth, atony Kishechnika.so the urogenital system : atony bladder.

Specific guidance

When treating hypertension may combine with rezerpinom and other hypotensive Programme (dose eight individually).

Patient interaction

Tricyclic antidepressants can reduce hypotension.

Precautions

In order to prevent the development of collapse ortostaticski need to stay patient in a horizontal position for a period of 2-2.5 hours after application.

Dosing and Administration

Inside (after meals), for 0,001-0,002 g 2-4 times a day for 3-6 weeks.

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