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Ubretid

See also Distigmine bromide

Roman name

Ubretid

The composition and the form of

1 tablet contains bromide distigmina 5 mg; blistere in 10 pcs. , in a box two blister.1 USD 1 ml solution for injection 0.5 or 1 mg; in a carton five vials.

Clinical pharmacology

Through 1-1.5 hrs after taking into increased secretion and improves the patient's general condition and irritative bowel mochetocnikov, bladder. Increased muscle blood reaches the maximum 10 hours and lasts for 20 hours; Skeletnuu tones muscles, with myasthenia significant effect appears in 1-2 days.

Indications

Postoperative atony paralysis and bowel occlusion (prevention and treatment), the postoperative atony bladder and mochetocnikov, functional deficiency pouches bladder and hypotension bladder (including neirogenny bladder), chronic gipotonicescie and atonicescie constipation, megakolon, means "poperechnopolostah muscles severe male (myasthenia gravis).

Pregnancy and lactation

Acceptable, but only on strict conditions.

Contraindications

Its wagotonia (prevailing tone parasimpaticescoy nervous system), with the phenomena expressed bradikardii, bronchial asthma, arterial hypotension, giperatidnosti gastric juice gipermotorika blood, plenty slunootdelenie, gipertonus intestine, biliary and urinary tract infections, hospital stomach disease, inflammatory bowel disease, posleoperazionny kriz Stroke, chronic heart failure, myocardial infarction, human peripheral blood circulation, increased muscle strength, tetania, epilepsy, parkinsonism.

Side-Effects

Nausea, vomiting, diarrhea, stomach cramps, the eye of stomach or intestinal peristalsis, bronhospazm, aetiology (less than 60 strokes per minute), narrowing missed, the odor, gipersalivacia, slezotechenie, muscle cramps, tremor, difficulty glotania etc. of gipervozbujdenia voice and n-holinoretseptorov.

Patient interaction

Effect weaken antiholinergicakie (atropine), psychotropic, antihistamines, kurarepodobne preparations aminoglikozida (the weak miorelaksantnam act).

Overdosing

Symptoms associated with the operation of holinomimeticski, nausea, vomiting, diarrhoea, pain in the abdomen, bronhospazm, aetiology, failure, 08.05.2005 sweat, etc. Treatment-in / in or s / to give atropine dose of 0.5-1 mg.

Precautions

During the treatment to refrain from driving, maintenance machinery (slows down your reaction). Be wary appoint women with temporary dismenoreei (can cause bleeding, such as menstrual). If in the application of the pill is not seen as a result of prior or simultaneous mealtimes escape readmitting preparation for a few hours (because of a possible cumulation).

Storage conditions

Schedule A. In the dark place at a temperature of 15-25 ° C

Shelf life

5 years

The registration

015672/01

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