Oftan pilocarpine

Roman name

Oftan Pilocarpin

Characteristics

Holinergicescoe means of stimulating muskarinove receptors.

Pharmacokinetics

It permeates through rogovitsu, C_max in big watery eyes done in 30 minutes. Binds many tissues eye T_1/2 of eyes, ranging from 1.5 to 2.5 hours There is metabolized into watery moisture, arrived at the capital.

Farmakodinamika

In open-glaucome decline vnutriglaznogo pressure due mainly to facilitate the movement of watery moisture. In zakratougolna form narrowing maybe leads to the disclosure raduzhno-rogovicnogo angle and increase the outflow watery moisture. Effects of the drug on inner pressure continues from 4 to 2:00 pm

Indications

Primary otkratougolnaya glaucoma, glaucoma zakratougolnaya, incl. treatment of acute attack zakratougolna glaucoma. In a survey conducted eyes to narrow missed, for the treatment of the symptoms caused by midriatikov (medication has the opposite midriatikam and means relaxing resnicnuu muscle).

Pregnancy and lactation

It is considered relatively safe during pregnancy and while breastfeeding, although such clinical tests have been carried out.

Contraindications

Cristina, iridotsyklit and other conditions that would not be reduced pupil (eg after surgery to eye, except when it is necessary to narrow zracek immediately after the operation, in order to avoid falling into sinehi) гиперчувствительност ь to pilocarpino to apply caution in patients with otslaka retinal disease in the young patients with miopiei high.

Patient interaction

It is combined with бета-адреноблокатора��и and other hypotensive drugs for the treatment of glaucoma. Perhaps a combination of the pesticides in carboangidraza kupirovanii acute attack zakratougolna glaucoma. Atropine and other m-holinoblokatora - pilocarpina antagonists. Tricyclic antidepressants, derivatives fenotiazina, hlorprotiksen, clozapin reduce and antiholinesteraznae means m-holinomimeticescuu increased activity. During general anaesthesia with ftorotana may decline AD and aetiology.

Precautions

There is a need to be careful when driving at night or in low light.

Storage conditions

List B. The temperature 2-15 ° C

Shelf life

2 years. After opening bottle-1 month

The registration

015372/01

The drug forms

Transparent colourless solution.

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